Development of a new health-related quality of life measure for people with diabetes who experience hypoglycaemia: the Hypo-RESOLVE QoL

Carlton, Jill; Powell, Philip A.; Broadley, Melanie; de Galan, Bastiaan E.; Heller, Simon; Comins, Jonathan; Rosilio, Myriam; Pouwer, Frans; Gall, Mari-Anne; Child, Christopher J.; McCrimmon, Rory J.; Rowen, Donna

doi:10.1007/s00125-024-06182-9

Table 4 Pearson and point-biserial correlations between HRQoL measures and background characteristics (Stage 3)

From: Development of a new health-related quality of life measure for people with diabetes who experience hypoglycaemia: the Hypo-RESOLVE QoL

Measure	(1) Hypo-RESOLVE QoL total	(2) Hypo-RESOLVE QoL physical	(3) Hypo-RESOLVE QoL social	(4) Hypo-RESOLVE QoL psychological	(5) Hypoglycaemia QoL VAS (4 weeks)	(6) DIDP (4 weeks)	(7) HypoA-Q impaired awareness	(8) EQ-5D-5L
(1) Hypo-RESOLVE QoL total	–	0.89	0.83	0.92	0.59	−0.55	−0.23	0.46
(2) Hypo-RESOLVE QoL physical	0.89	–	0.64	0.70	0.52	−0.47	−0.17	0.34
(3) Hypo-RESOLVE QoL social	0.83	0.64	–	0.69	0.49	−0.46	−0.18	0.32
(4) Hypo-RESOLVE QoL psychological	0.92	0.70	0.69	–	0.56	−0.53	−0.23	0.49
(5) Hypoglycaemia QoL VAS (4 weeks)	0.59	0.52	0.49	0.56	–	−0.42	−0.18	0.39
(6) DIDP (4 weeks)	−0.55	−0.47	−0.46	−0.53	−0.42	–	0.07	−0.35
(7) HypoA-Q impaired awareness	−0.23	−0.17	−0.18	−0.23	−0.18	0.07	–	−0.17
(8) EQ-5D-5L	0.46	0.34	0.32	0.49	0.39	−0.35	−0.17	–
(9) HypoA-Q / no. of hypoglycaemia events (past week)	−0.22	−0.21	−0.24	−0.18	−0.21	0.18	0.13	−0.01
(10) Age (years)	0.27	0.28	0.25	0.21	0.13	−0.14	0.10	−0.11
(11) Identifies as a woman	−0.13	−0.15	−0.06	−0.12	−0.04	0.06	−0.01	−0.05
(12) Non-White ethnicity	−0.02	−0.02	−0.03	−0.02	−0.07	0.01	0.00	−0.03
(13) Has English as a first language	−0.01	−0.02	−0.02	0.01	−0.01	0.01	0.03	−0.02
(14) Has a degree	0.03	0.01	0.01	0.05	0.03	0.06	−0.03	0.17
(15) Is employed	0.01	−0.04	−0.03	0.05	0.07	0.00	−0.16	0.32
(16) Has diabetes other than type 1	0.02	0.08	0.10	−0.03	−0.02	−0.02	−0.01	−0.30
(17) Diabetes duration (years)	0.07	0.08	0.05	0.05	0.00	0.01	0.17	−0.06
(18) Insulin duration (years)	0.08	0.08	0.05	0.06	0.00	0.00	0.17	−0.04
(19) Frequency will run high	−0.33	−0.32	−0.29	−0.30	−0.23	0.18	0.04	−0.12
(20) Has a comorbid condition	−0.09	−0.03	−0.02	−0.15	−0.11	0.10	0.13	−0.33
(21) Gold Score	−0.21	−0.17	−0.15	−0.20	−0.20	0.11	0.71	−0.16
(22) Uses insulin	−0.04	−0.07	−0.07	−0.03	0.00	0.09	0.00	0.10
(23) Uses CGM	−0.08	−0.13	−0.14	−0.03	−0.02	0.06	0.07	0.19

CGM, continuous glucose monitor

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