Fig. 1

Formation of the study cohort. Flowchart illustrates the formation of the study cohort. *Timepoint at which FLRs were taken; 12 months (n = 965), 24 months (n = 230), 36 months (n = 112), 48 months (n = 20)

Formation of the study cohort. Flowchart illustrates the formation of the study cohort. *Timepoint at which FLRs were taken; 12 months (n = 965), 24 months (n = 230), 36 months (n = 112), 48 months (n = 20)