Table 2 Non-steroidal anti-inflammatory drugs (NSAIDs) and adverse cardiovascular events in patients with gout
Outcome | Odds ratio (95% confidence interval) comparing use with non-use | |||
|---|---|---|---|---|
Any NSAID | Ibuprofen | Naproxen | Diclofenac | |
Myocardial infarction | 0.91 (0.84–0.99) | 0.98 (0.88–1.10) | 0.73 (0.52–1.00) | 0.96 (0.81–1.14) |
Ischemic stroke | 0.88 (0.81–0.95) | 0.86 (0.77–0.96) | 0.90 (0.67–1.23) | 1.04 (0.88–1.23) |
Congestive heart failure | 0.89 (0.83–0.94) | 0.94 (0.86–1.02) | 0.81 (0.63–1.04) | 0.89 (0.77–1.02) |
Atrial fibrillation/flutter | 0.80 (0.75–0.85) | 0.82 (0.75–0.90) | 0.85 (0.66–1.11) | 0.83 (0.71–0.96) |
Cardiovascular death | 0.60 (0.56–0.65) | 0.67 (0.61–0.74) | 0.53 (0.40–0.71) | 0.87 (0.76–0.99) |