No evidence of differential impact of sunflower and rapeseed oil on biomarkers of coronary artery disease or chronic kidney disease in healthy adults with overweight and obesity: result from a randomised control trial

Table 4 Urinary proteomic biomarker scores for coronary artery disease (CAD238) and chronic kidney disease (CKD273) at week 0, 6 and 12 of the intervention

	Rapeseed oil (n = 21)		Sunflower oil (n = 21)		Control (n = 19)		p score¹	p change²
	Score	Δ (change)	Score	Δ (change)	Score	Δ (change)	p score¹	p change²
CAD238
Baseline	− 0.4 ± 0.2	–	− 0.4 ± 0.3	–	− 0.3 ± 0.3	–	0.37	–
Week 6	− 0.4 ± 0.2	0.0 ± 0.3	− 0.3 ± 0.3	0.0 ± 0.3	− 0.4 ± 0.3	− 0.1 ± 0.3	0.17	0.07
Week 12	− 0.5 ± 0.2	− 0.1 ± 0.2	− 0.4 ± 0.2	− 0.1 ± 0.3	− 0.4 ± 0.2	− 0.1 ± 0.3	0.63	0.95
CKD273
Baseline	− 0.4 ± 0.2	–	− 0.5 ± 0.2	–	− 0.4 ± 0.3	–	0.96	–
Week 6	− 0. 5 ± 0.1	− 0.1 ± 0.3	− 0.5 ± 0.3	0.0 ± 0.2	− 0.4 ± 0.3	0.0 ± 0.3	0.06	0.10
Week 12	− 0.4 ± 0.2	0.0 ± 0.3	− 0.5 ± 0.3	0.0 ± 0.3	− 0.4 ± 0.2	0.0 ± 0.3	0.99	0.79

Data are presented as mean ± SD
¹One-way ANOVA investigating scoring differences between groups at baseline. One-way ANCOVA investigated scoring differences between groups at weeks 6 and 12, after adjusting for baseline
²One-way ANOVA was used to investigate differences between groups in mean scoring change from baseline at weeks 6 and 12
*Indicates a significant difference from baseline (p < 0.05; none observed in this table)