Table 3 Univariate and multivariate analyses to assess whether there is an association between Alzheimer’s and T. gondii seropositivity
From: Association between Toxoplasma gondii seropositivity and Alzheimer’s disease: a case-control study
Study participants | Toxoplasma seropositive Number (%) | Toxoplasma seronegative Number (%) | Univariate analyses ORs (95% CIs) | Multivariate analyses ORs (95% CIs) * | Hosmer and Lemeshow test – adjusted model |
|---|---|---|---|---|---|
Total patients with Alzheimer’s disease | 70 (77.8) | 20 (22.2) | 0.43 (0.18, 0.98) | 0.35 (0.14, 0.92) | Pearson chi2 = 254.35, p < 0.001 |
Healthy controls | 81 (89) | 10 (11) | Ref | Ref | |
Mild Alzheimer’s disease | 41 (78.8) | 11 (21.2) | Ref | Ref | Pearson chi2 = 368.42, p < 0.001 |
Moderate to severe Alzheimer’s disease | 29 (76.3) | 9 (23.7) | 0.50 (0.25, 1.02) | 0.44 (0.20, 0.97) |