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Fig. 6 | Acta Neurochirurgica

Fig. 6

From: Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

Fig. 6

A A correlation matrix visualizes the relationships of following parameters among all studies included in the systematic review (n = 28): The following parameters are used here: Patient sample size (“Sample”), mean age of the patients (“Age”), proportion of patient sample being female (“Females”), pre-existing diabetes mellitus (“DM”), pre-existing arterial hypertension (“HTN”), gait deficits (“Gait- “ or “Gaitdef”), cognitive deficits (“Cognition- “ or “Cognitiondef”), urinary dysfunction (“Urine- “ or “Urinedef”), mean proportion of patients being shunt-responsive (“S-R”), and proportion of complications (“Complic.” or “Complic”), mean patient scores on the Mini Mental State Exam (“MMSE”). Furthermore, mean patient scores for Evan’s Index (“EI”) and mean values for Callosal Angle (“CA”). The legend bar at the right of the matrix explains the coloring. One asterisk (*) indicates a statistical significance of p < 0.05, two asterisks (**) indicate p < 0.01, three asterisks (***) indicate p < 0.001. B A heatmap based on machine learning imputation visualizes and compares the occurrence of the same parameters as A among all studies included in the systematic review (n = 28). The respective legend is shown at the bottom right corner. Turquoise coloring indicates minimum values (“min”), white coloring indicates medium values, and pink coloring indicated maximum values. Clustering is shown above and to the left of the graph

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