Table 10 The use of flow void for prediction of shunt response in iNPH
Study | Sample size | Radiological methodology | Cutoff specification | Image specification | Image plane | Main reported outcomes |
|---|---|---|---|---|---|---|
Agerskov et al. [2] | n = 168 | •Void in Cerebral aqueduct and fourth ventricle. Evaluated using ordinal scale graded 0–3 | •N/A | •MRI 1.5 T. T1-weighted images | •Coronal slice | •0% of patients had grade 0, 30% had grade 1, 42% had grade 2 and 28% had grade 3 •There was no significant difference, in each grade, between SR and SNR |
Virhammar et al. [60] | n = 36 | •Ordinal scale: Graded 0–3. 0 = no flow, 1 = flow void only in the aqueduct, 2 = flow void in the aqueduct and upper half of the fourth ventricle, 3 = flow that extends to caudal part 4th ventricle | •N/A | •T2-weighted images | •Sagittal images without flow compensation | •OR between SR and SNR: 4.25 (0.75–23.97), p = 0.1) was not significant |