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Table 11 The use of bulging of the lateral ventricular roof for prediction of shunt response in iNPH

From: Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

Study

Sample size

Radiological methodology

Cutoff specification

Image specification

Image plane

Main reported outcomes

Narita et al., 2016[41]

n = 103

•Presence (1) or absence (0) noted at level above top of thalamus

•N/A

•3D T1-weighted MRI obtained with a Signa 1.5 T MR imaging unit

•Transverse plane

•No significant association with post-surgical improvement reported. (Regression coefficient for total score, gait, cognitive, urinary subsections, TUG and MMSE was 0.47, 0.31, 0.11, 0.05, 2.20, 1.20 respectively p > 0.1)

Virhammar et al., 2014 [60]

n = 108

•On roof of lateral ventricles. Graded as present or absent

•N/A

•T2 Flair, T1-weighted MRI. (9% of patients on 3 T scanner; 70% on a 1.5 T scanner, 14% on a 1 T scanner and 7% on a 0.5 T scanner

•Sagittal

•OR between SR and SNR: 3.22 (0.97–10.69), p = 0.055) was not significant

  1. Studies included assessing the use of any advanced imaging radiological marker as predictor of shunt responsiveness. SR, shunt response; S-NR, shunt non-response; FLAIR, fluid-attenuated inversion recovery; MMSE, mini mental state examination; TUG, timed up and go test
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