Table 6 The use of Sylvian fissure size for prediction of shunt response in iNPH
Study | Sample size | Radiological methodology | Cutoff specification | Image specification | Image plane | Main reported outcomes |
|---|---|---|---|---|---|---|
Poca et al., 2004 [45] | n = 43 | •Sylvian fissures were categorized into normal, obliterated or dilated | •N/A | •CT | •N/A | •13 patients had normal fissures, 29 had dilated fissures while 1 was obliterated. Patients with normal fissures showed greater improvement in Trail Making Test B (chi-square test: 7.18, p = 0.007) |
Agerskov et al., 2019 [2] | n = 168 | •Graded from 0–2 | •N/A | •MRI 1.5 T. trans-axial T1-weighted images | •Axial slice | •28% of patients had grade 0, 45% grade 1 and 27% grade 2 •There was no difference, in each grade, between SR and SNR |
Narita et al., 2016 [41] | n = 103 | •Graded on visual ordinal scale from 0–3: 0 – narrowed, 1- normal; 2—mildly dilated, and 3—severely dilated | •N/A | •3D T1-weighted MRI obtained with a Signa 1.5 T MR imaging unit | •Transverse and axial | •Simple linear regression analysis: There was an association between Sylvian fissure dilation and change in iNPHGS gait (B = 0.59, R2 = 0.08, p = .029). There was no association with total score, cognitive or urinary subjection, or TUG or MMSE. (1.03, − 0.09, 0.53, − 2.65, 1.00 respectively) |
Virhammar et al., 2014 [60] | n = 108 | •Ordinal scale: Graded 0–3 evaluated at level of central part of brain stem, angulated along brain stem •Height: Mean (mm) measurement at 5 different locations perpendicular to fissure direction in midpoint between skull and insular cortex | •N/A | •T2 Flair, T1-weighted MRI. (9% of patients on 3 T scanner; 70% on a 1.5 T scanner, 14% on a 1 T scanner and 7% on a 0.5 T scanner | •Ordinal: Coronal •Height: Sagittal | •Ordinal: OR between SR and SNR [ 1.35 (0.57–3.21), p = 0.5] was not significant •Height: OR between SR and SNR [1.20 (0.59–2.43), p = 0.62] was not significant |