Table 8 The use of high-convexity tightness alone for prediction of shunt response in iNPH
Study | Sample size | Radiological methodology | Cutoff specification | Image specification | Image plane | Main reported outcomes |
|---|---|---|---|---|---|---|
Narita et al. [41] | n = 103 | •Observed in 4 uppermost contiguous transverse sections and 3 contiguous coronal sections anterior to and on the posterior commissure. Graded on ordinal scale from 0–3 | •N/A | •3D T1-weighted MRI obtained with a Signa 1.5 T MR imaging unit | •Transverse and Coronal | •Simple linear regression analysis: presurgical high-convexity tightness was associated with change in iNPHGS total score (regression coefficient [B] = 1.23, coefficient of determination [R2] = 0.13, p = .004), change in iNPHGS gait score (B = 0.59, R2 = 0.16, p = .002), and change in MMSE (B = 2.56, R2 = 0.17, p = 0.001) •Multiple linear regression analysis: high convexity tightness predicted change in the iNPHGS total score (B = 0.99, R2 = 0.24, p = .017) and the gait score (B = 0.52, R2 = 0.21, p = .006) |
Virhammar et al. [60] | n = 108 | •Graded 0–2 •0 = Normal or wider than normal •1 = slight compression •2 = definitive compression | •N/A | •T2 Flair, T1-weighted MRI. (9% of patients on 3 T scanner; 70% on a 1.5 T scanner, 14% on a 1 T scanner and 7% on a 0.5 T scanner | •Coronal and transverse plane | •OR between SR and SNR [1.43 (0.84–2.46), p = 0.2] |