Appropriateness of the institute certification system for esophageal surgeries by the Japan Esophageal Society: evaluation of survival outcomes using data from the National Database of Hospital-Based Cancer Registries in Japan

Table 3 Univariate Cox proportional hazard analysis of survival

Cox analyses	Univariable
Factor	HR	p	95% CI
Age ≧70 vs. < 70	1.45	< 0.001	1.28	1.64
Male vs. female	1.47	< 0.001	1.22	1.76
T3–4 vs. Tis-2 (n = 2066)^a	2.28	< 0.001	2.01	2.57
N1–3 vs. N0 (n = 2076)^a	2.09	< 0.001	1.85	2.37
M1 vs. M0 (n = 2077)	2.31	< 0.001	1.92	2.79
Clinical stage (UICC, n = 2069)^a
cStage 0	0.34	0.27	0.01	1.95
cStage I	ref
cStage II	2.28	< 0.001	1.88	2.77
cStage III	3.72	< 0.001	3.08	4.52
cStage IV	5.31	< 0.001	4.15	6.78
AIBCES vs. non-AIBCES	0.79	< 0.001	0.70	0.89
Adjuvant therapy (n = 2133)^a
No radiation or chemotherapy	ref
+Radiation therapy	5.09	< 0.001	3.56	7.09
+Chemotherapy	1.34	< 0.001	1.17	1.52
+Radiation and chemotherapy	2.33	< 0.001	1.95	2.77