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Table 2 Course of disease

From: Does positive MGMT methylation outbalance the limitation of subtotal resection in glioblastoma IDH-wildtype patients?

 

Cohort

n = 81 (%)

MGMT positive

n = 31 (%)

MGMT negative

n = 50 (%)

Treatment response (TR) n = 23

   

 Complete remission (CR)

2 (8.7)

2 (12.5)

0 (0)

 Partial remission (PR)

2 (8.7)

1 (6.3)

1 (14.3)

 Stable disease (SD)

19 (82.6)

13 (81.2)

6 (85.7)

Progressive disease (PD) n = 58

   

 RANO-criteria

24 (41.4)

5 (33.3)

19 (44.2)

 18F-FET-PET

9 (15.5)

9 (6.7)

8 (18.6)

 Surgery

25 (43.1)

25 (43.1)

16 (37.2)

  1. Treatment response dependent from MGMT methylation status, and diagnosis of progressive disease