Fig. 4

Single-cell data set GSE149614 FRG cell scoring and functional enrichment analysis of high-scoring cell populations. A FRG scores among cell subpopulations (AUC), with lighter colors indicating higher scores, where monocytes and macrophages had the highest mean scores. B Bubble plot of KEGG results for DEGs between monocytes and macrophages, with closer colors to red indicating smaller p and larger bubbles indicating more DEGs enriched within that pathway. C BP, CC, and MF enrichment results of GO analysis of DEGs between monocytes and macrophages presented as bubble plots, with colors closer to red indicating smaller p and larger bubbles indicating more DEGs enriched within that pathway. AUC area under the curve, KEGG Kyoto Encyclopedia of Genes and Genomes, DEGs differentially expressed genes, GO Gene Ontology, BP biological process, CC cellular component, MF molecular function