Fig. 3
From: Altered Extracellular Vesicle MicroRNA Expression in Ischemic Stroke and Small Vessel Disease
Expression of miRNAs in EV from stroke patients. The expression of hsa-miR-17-5p (a), hsa-miR-20b-5p (b), hsa-miR-27b-3p (c) and hsa-miR-93-5p (d) was profiled in EV isolated from stroke patients (n = 139) and compared to expression in non-stroke patients (n = 34). Change in miRNA expression was assessed at 48 h post-stroke by qRT-PCR and RQ calculated from ΔΔCt following normalisation to a spike housekeeper miRNA, cel-miR-39, and compared to the control, non-stroke patients. Data are presented as RQ ± RQmax/RQmin. Probability values were calculated using unpaired Student’s t test vs. non-stroke control patients, *p < 0.05.