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Table 2 Complication among patients with influenza during the follow-up period

From: Predictors and Outcomes of Hospitalization for Influenza: Real-World Evidence from the United States Medicare Population

 

Hospitalized patients

Non-hospitalized

(N = 16,784)

All hospitalized (N = 8474)

High-riska (N = 8127)

General wardb (N = 5129)

ICUc (N = 2547)

MVd (N = 961)

Complications, n (%)

 Acute kidney failure

2212 (26.1%)

2165 (26.6%)

1075 (21.0%)

916 (36.0%)

439 (45.7%)

155 (0.9%)

 Sinusitis

378 (4.5%)

350 (4.3%)

245 (4.8%)

103 (4.0%)

37 (3.9%)

1400 (8.3%)

 Encephalomyelitis

11 (0.1%)

9 (0.1%)

6 (0.1%)

1 (0.0%)

3 (0.3%)

4 (0.0%)

 Guillain–Barré syndrome

458 (5.4%)

445 (5.5%)

268 (5.2%)

153 (6.0%)

48 (5.0%)

171 (1.0%)

 Ischemic heart disease

3625 (42.8%)

3609 (44.4%)

2027 (39.5%)

1221 (47.9%)

485 (50.5%)

2273 (13.5%)

 Kidney failure

2327 (27.5%)

2278 (28.0%)

1143 (22.3%)

955 (37.5%)

451 (46.9%)

221 (1.3%)

 Acute myocarditis

5 (0.1%)

5 (0.1%)

3 (0.1%)

2 (0.1%)

0 (0.0%)

1 (0.0%)

 Myositis

325 (3.8%)

300 (3.7%)

199 (3.9%)

94 (3.7%)

39 (4.1%)

599 (3.6%)

 Pneumonia

4977 (58.7%)

4796 (59.0%)

2805 (54.7%)

1742 (68.4%)

775 (80.6%)

1647 (9.8%)

 Respiratory failure

2552 (30.1%)

2460 (30.3%)

909 (17.7%)

1344 (52.8%)

864 (89.9%)

66 (0.4%)

 Rhabdomyolysis

163 (1.9%)

157 (1.9%)

81 (1.6%)

63 (2.5%)

23 (2.4%)

14 (0.1%)

 Sepsis

1279 (15.1%)

1209 (14.9%)

682 (13.3%)

486 (19.1%)

174 (18.1%)

53 (0.3%)

 Stroke

574 (6.8%)

570 (7.0%)

294 (5.7%)

229 (9.0%)

73 (7.6%)

227 (1.4%)

 Otitis

80 (0.9%)

76 (0.9%)

56 (1.1%)

16 (0.6%)

5 (0.5%)

316 (1.9%)

 Upper and lower respiratory tract infection

5328 (62.9%)

5111 (62.9%)

3124 (60.9%)

1750 (68.7%)

724 (75.3%)

6055 (36.1%)

  1. ICU intensive care unit, MV mechanical ventilation
  2. aPatients were identified as high risk if they were aged 65+ years at the time of influenza diagnosis, had a diagnostic code for chronic lung disease (asthma, chronic obstructive pulmonary disease, or cystic fibrosis), cardiovascular or cerebrovascular conditions (congenital heart disease, congestive heart failure, coronary artery disease, or stroke), and a weakened immune system (HIV, cancer, chronic liver or kidney disease, or chronic systemic steroids) during the baseline period or on the diagnosis date
  3. bPatients that did not use services in the ICU or MV during the index hospitalization
  4. cPatients that used services in the ICU during index hospitalization. ICU and MV are not mutually exclusive
  5. dPatients that used MV during index hospitalization. ICU and MV are not mutually exclusive