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Fig. 5: ARHGEF2 as a new target for promoting angiogenesis. | Cell Death & Disease

Fig. 5: ARHGEF2 as a new target for promoting angiogenesis.

From: ARHGEF2/EDN1 pathway participates in ER stress-related drug resistance of hepatocellular carcinoma by promoting angiogenesis and malignant proliferation

Fig. 5: ARHGEF2 as a new target for promoting angiogenesis.

A The cell-conditioned media of HepG2/shNC and HepG2/shARHGEF2 cells were collected for tube formation assay. B Representative images of CAM blood vessels stimulated with cell-conditioned media from the indicated cells. C, D The migration and invasion ability of CM-treated HUVEC cells were detected by wound-healing assay and transwell assay. E–H The cell-conditioned media of MHCC97H/Vector and MHCC97H/ARHGEF2 cells were collected for tube formation assay (E), CAM assay (F), wound-healing assay (G) and transwell assay (H).

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