Figure 2

Box plots show miRNA expression levels measured in the three study groups, expressed as normalised values using global normalisation. The horizontal line denotes the median value, the box encompasses the upper and lower quartiles, whiskers show the range, and the plus symbol denotes the mean. A nonparametric Kruskal-Wallis test was carried out. If the Kruskal-Wallis test was significant, post hoc tests were carried out, to adjust p-values for multiple testing using the Benjamini-Hochberg method. The results of these are denoted in the plot with horizontal bars and asterisks (*P = 0.01–0.05; **P < 0.01). These data represent results of duplicate experiments, with 5 animals in each group.