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Table 5 OR and 95% CI of GGT ≥75th associated with major CRFs and clustered risk factors. Age, UA, alcohol, ethnicity, and all other risk factors were adjusted when estimating odds ratios (ORs) with 95% confidence intervals (CIs) of each variable.

From: Serum Gamma-Glutamyltransferase Levels are Associated with Cardiovascular Risk Factors in China: A Nationwide Population-Based Study

CRFs

Men

Women

Unadjusted OR (95% CI) GGT ≥75th

Adjusted OR (95% CI) GGT ≥75th

Unadjusted OR (95% CI) GGT ≥75th

Adjusted OR (95% CI) GGT ≥75th

Dyslipidemia

4.530 (4.084–5.025)*

3.895 (3.487–4.352)*

3.439 (3.157–3.745)*

2.187 (1.985–2.408)*

Hypertension1

1.999 (1.820–2.195)*

1.709 (1.536–1.901)*

2.498 (2.280–2.738)*

1.483 (1.334–1.649)*

Hypertension2

2.515 (2.294–2.757)*

2.122 (1.920–2.344)*

2.251 (2.074–2.445)*

1.681 (1.537–1.839)*

Diabetes

2.365 (1.977–2.830)*

2.573 (2.1100–3.138)*

4.952 (4.076–6.016)*

2.904 (2.349–3,591)*

Current smoking

1.573 (1.439–1.720)*

1.325 (1.201–1.462)*

1.815 (1.452–2.267)*

1.365 (1.069–1.745)*

Overweight

3.739 (3.412–4.096)*

3.165 (2.859–3.504)*

3.219 (2.953–3.508)*

2.086 (1.896–2.295)*

clustered risk factors

   0

1 (ref)

1 (ref)

1 (ref)

1 (ref)

   1

2.334 (1.892–2.878)*

2.096 (1.685–2.606)*

2.804 (2.498–3.148)*

2.087 (1.841–2.366)*

   2

6.026 (4.936–7.356)*

4.853 (3.923–6.002)*

5.702 (5.052–6.437)*

3.412 (2.968–3.921)*

   ≥3

13.859 (11.360–16.907)*

10.843 (8.748–13.441)*

10.415 (9.013–12.036)*

5.344 (4.516–6.324)*

  1. *P < 0.05.
  2. 1OR and 95% CI of GGT ≥75th associated with hypertension defined with JNC7.
  3. 2OR and 95% CI of GGT ≥75th associated with hypertension defined with 2017 ACC/AHA.
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