Table 1 Baseline characteristics of the present study population (162 women with ovarian, tubal, and peritoneal cancer).
All (N = 162) | Relapse-free (N = 76) | Relapse (N = 86) | P-Value | |
|---|---|---|---|---|
Age at diagnosis, years | 52 (47–61) | 52 (47–61) | 52.5 (47–60) | 0.997 |
BMI, kg/m2 | 22.8 (21–24.8) | 22.7 (20.9–24.7) | 22.8 (21.2–25) | 0.900 |
FIGO stage | < 0.001* | |||
I | 13 (8.0%) | 12 (15.8%) | 1 (1.2%) | |
II | 45 (27.8%) | 25 (32.9%) | 20 (23.3%) | |
III | 67 (41.4%) | 28 (36.8%) | 39 (45.3%) | |
IV | 37 (22.8%) | 11 (14.5%) | 26 (30.2%) | |
Tumor origin | 0.974 | |||
Ovary | 143 (88.3%) | 67 (88.2%) | 76 (88.4%) | |
Fallopian tube | 12 (7.4%) | 7 (9.2%) | 5 (5.8%) | |
Peritoneum | 7 (4.3%) | 2 (2.6%) | 5 (5.8%) | |
CA125 at diagnosis, U/mL | 0.026* | |||
≤ 500 | 54 (33.3%) | 32 (42.1%) | 22 (25.6%) | |
≤ 1000 | 45 (27.8%) | 20 (26.3%) | 25 (29.1%) | |
≤ 2000 | 23 (14.2%) | 9 (11.8%) | 14 (16.3%) | |
> 2000 | 40 (24.7%) | 15 (19.7%) | 25 (29.1%) | |
Primary treatment | 0.032* | |||
NACT + IDS | 72 (44.4%) | 27 (35.5%) | 45 (52.3%) | |
PDS + ACT | 90 (55.6%) | 49 (64.5%) | 41 (47.7%) | |
Median number of chemotherapy cycles | 7 | 7.5 | 7 | 0.912 |
Surgical procedures | ||||
Pelvic lymphadenectomy | 65 (40.1%) | 32 (42.1%) | 33 (38.4%) | 0.630 |
Para-aortic lymphadenectomy | 26 (16.0%) | 12 (15.8%) | 14 (16.3%) | 0.933 |
Abdominal organ resection | 13 (8.0%) | 8 (10.5%) | 5 (5.8%) | 0.272 |
Distant metastases resection | 15 (9.3%) | 2 (2.6%) | 13 (15.1%) | 0.006* |
Operation time, min | 188 (150–236) | 188.5 (150–227.5) | 188 (150–238.5) | 0.930 |
Blood loss, mL | 200 (100–400) | 200 (100–400) | 200 (100–410) | 0.571 |
Surgical outcome | 0.008* | |||
RT = 0 | 100 (61.7%) | 54 (71.1%) | 46 (53.5%) | |
RT < 1 cm | 35 (21.6%) | 16 (21.1%) | 19 (22.1%) | |
RT ≥ 1 cm | 27 (16.7%) | 6 (7.9%) | 21 (24.4%) | |
Histologic grade | 0.006* | |||
High-grade serous | 127 (78.4%) | 52 (68.4%) | 75 (87.2%) | |
Low-grade serous | 15 (9.3%) | 12 (15.8%) | 3 (3.5%) | |
Serous not specified | 20 (12.3%) | 12 (15.8%) | 8 (9.3%) |