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Table 1 Statistically significant SNPs (P < 0.05) relevant to esophageal squamous cell carcinoma. In 2000 runs of 10-fold cross-validation, nine SNPs were found to be the esophageal squamous cell carcinoma relevant. They had frequencies greater than the critical value of 0.028 at the 5% level of significance (P < 0.05).

From: Decision Forest Analysis of 61 Single Nucleotide Polymorphisms in a Case-Control Study of Esophageal Cancer; a novel method

No

SNPs

Frequency

Gene function

 

Gene

RS number

  

1

GADD45B

E1122

0.186

DNA repair

2

NQO1

rs1800566

0.069

Phase II

3

adh1b_55

 

0.064

Alcohol-related

4

ERCC5

rs17655

0.064

DNA repair

5

COMT

rs4818

0.052

Phase II

6

GADD45B

rs14384

0.049

DNA repair

7

ercc5_55

 

0.048

DNA repair

8

CYP1A1

rs1048943

0.035

Phase I

9

GPX1_

rs1800668

0.030

Phase II

  1. RS – Reference SNP
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