Table 6 Cardiac level (pg/mg protein) of inflammatory cytokine (IL-1beta, IL-6, TNF-alpha and MCP-1), and anti-inflammatory cytokine (IL-4 and IL-10) in non-diabetic (Non-DM), diabetic mice consumed normal diet (DM), 2% caffeic acid (CA) or ellagic acid (EA) at 12 week.
Non-DM | DM | DM+CA | DM+EA | |
|---|---|---|---|---|
IL-1beta | 15 ± 2a | 331 ± 26c | 234 ± 25b | 227 ± 23b |
IL-6 | 18 ± 3a | 411 ± 30d | 323 ± 28c | 226 ± 26b |
TNF-alpha | 19 ± 4a | 386 ± 21d | 305 ± 25c | 245 ± 19b |
MCP-1 | 16 ± 3a | 278 ± 22d | 225 ± 16c | 192 ± 14b |
IL-4 | 14 ± 4a | 230 ± 24b | 227 ± 21b | 219 ± 26b |
IL-10 | 17 ± 3a | 209 ± 30b | 198 ± 19b | 204 ± 29b |