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Table 1 TCP-increase for high sensitivity of choline PET, low whole prostate dose, high γ50(ASTRO consensus) and Fowler's α/β

From: Choline PET based dose-painting in prostate cancer - Modelling of dose effects

α [Gy-1]

α/β [Gy]

γ50

Det. rate PET [%]

Dose [Gy]

SIB [Gy]

Single dose [Gy]

TCPconv [%]

TCP Increase [%]

0.04

1.5

2.2

81

74

90

2

67.3

23.1

  1. Calculation of the increase in TCP with whole prostate dose of 74 Gy after boosting choline PET positive regions within the prostate up to 90 Gy. α and α/β are estimated from Fowler's data and γ50 from Cheung's data (ASTRO definition). For choline PET a high sensitivity was used.
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