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Table 3 TCP-increase for low sensitivity of choline PET, high whole prostate dose, low γ50(CN + 2 definition) and Fowler's α/β

From: Choline PET based dose-painting in prostate cancer - Modelling of dose effects

α [Gy-1]

α/β [Gy]

γ50

Det. rate PET [%]

Dose [Gy]

SIB [Gy]

Single dose [Gy]

TCPconv [%]

TCP Increase [%]

0.04

1.5

1.4

64

78

90

2

97.0

1.4

  1. Calculation of the TCP-increase after boosting choline PET positive regions within the prostate up to 90 Gy; the whole organ dose was set to 78 Gy. α/β is estimated from Fowler's data and γ50 from Cheung's data (CN + 2 definition). For choline PET a low sensitivity was used.
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