Table 5 Distribution of genotype and allele frequencies of the TGF-β1 at codon 25*G/C polymorphism in healthy controls (C), T1DM subjects (P), diabetic retinopaths (DR), nephropaths (DN), neuropaths (DNU) and complication free (CF) group*
From: TGF-β1 and IGF-I gene variations in type 1 diabetes microangiopathic complications
TGF-β1 codon 25* G/C | C n (%) | P n (%) | DR n (%) | DN n (%) | DNU n (%) | CF n (%) |
|---|---|---|---|---|---|---|
Genotype | ||||||
GG | 97 (81.5) | 201 (81) | 104 (77) | 68 (79) | 65 (79.3) | 83 (84.7) |
GC | 21 (17.6) | 44 (17.8) | 28 (20.8) | 17 (19.8) | 16 (19.5) | 15 (15.3) |
CC | 1 (0.9) | 3 (1.2) | 3 (2.2) | 1 (1.2) | 1 (1.2) | 0 (0.00) |
Allele | ||||||
G | 215 (90.3) | 446 (90) | 236 (87.4) | 153 (89) | 146 (89) | 181 (92.3) |
C | 23 (9.7) | 50 (10) | 34 (12.6) | 19 (11) | 18 (11) | 15 (7.7) |