Table 7 Multivariate analysis of factors associated with En bloc resection, complete resection, and procedure-related perforation
Variables | En bloc resection | Complete resection | Perforation | |||
|---|---|---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
Age | 1.009 (0.921–1.105) | 0.844 | 0.9991 (0.944–1.041) | 0.713 | 1.029 (0.948–1.116) | 0.494 |
Tumor location | 0.950 | 0.376 | 0.647 | |||
Upper thoracic | 1 | 1 | 1 | |||
Middle thoracic | N/A | 0.998 | 0.822 (0.171–3.959) | 0.807 | 0.483 (0.034–6.948) | 0.592 |
Lower thoracic | N/A | 0.998 | 1.203 (0.276–5.240) | 0.805 | 0.259 (0.020–3.309) | 0.298 |
Esophagogastric Jx | N/A | 1.000 | 0.140 (0.007–2.640) | 0.189 | N/A | 0.999 |
Tumor morphology | 0.734 | 0.955 | 0.933 | |||
IIa | 1 | 1 | 1 | |||
IIb | 4.775 (0.318–71.736) | 0.258 | 0.830 (0.253–2.728) | 0.759 | N/A | 0.998 |
IIc | N/A | 0.998 | 1.063 (0.225–5.030) | 0.939 | N/A | 0.998 |
Mixed | N/A | 1.000 | 0.511 (0.024–10.810) | 0.666 | N/A | 1.000 |
Gross tumor size (cm) | 0.294 (0.063–1.374) | 0.120 | 1.320 (0.630–2.768) | 0.462 | 0.907 (0.236–3.488) | 0.888 |
Resected specimen size (cm) | 1.147 (0319–4.126) | 0.834 | 0.475 (0.228–0.989) | 0.047 | 1.926 (0.580–6.397) | 0.285 |
Depth of tumor invasion | 0.744 | 0.228 | 0.924 | |||
Mucosal cancer | 1 | 1 | 1 | |||
SM invasion | 1.467 (0.147–14.623) | 0.567 (0.226–1.427) | 0.916 (0.150–5.596) | |||
Experience of endoscopist | 0.098 | 0.146 | 0.052 | |||
First 10 esophageal ESDs | 1 | 1 | 1 | |||
Further esophageal ESDs | 0.226 (0.039–1.315) | 0.513 (0.208–1.262) | 0.289 (0.082–1.011) | |||
Method of sedation | 0.996 | 0.011 | 0.030 | |||
Conscious sedation | 1 | 1 | 1 | |||
General anesthesia | N/A | 3.401 (1.317–8.785) | 0.067 (0.006–0.775) | |||