Skip to main content
Account

Table 4 Unadjusted and adjusteda odds ratio (OR) comparing estimated risks of each perinatal outcome at < 18, 18–23, 60–119, and ≥ 120 months interpregnancy intervals with estimated risks following 24–59 months intervals, stratified by maternal age at current delivery

From: Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China’s two-child policy

Outcome

Interpregnancy Interval, OR (95% CI)

   

< 18 months

18–23 months

24–59 months

60–119 months

≥ 120 months

 

Unadjusted

Adjusteda

p-valuea

Unadjusted

Adjusteda

p-valuea

 

Unadjusted

Adjusteda

p-valuea

Unadjusted

Adjusteda

p-valuea

Small-for-gestational age

             

All women

0.70

(0.31–1.37)

0.62 (0.28–1.28)

0.250

1.10 (0.55–1.99)

1.04

(0.53–1.93)

0.910

1.0

1.02 (0.73–1.44)

1.00

(0.69–1.43)

0.986

1.97 (1.33–2.93)

1.85

(1.11–3.05)

0.018

Maternal age, years

             

≤ 29

0.83

(0.27–2.12)

0.75

(0.24–1.98)

0.582

1.22 (0.40–3.14)

1.21

(0.39–3.14)

0.712

1.0

3.17 (1.65–6.19)

3.16

(1.62–6.30)

< 0.001

/

/

/

30–34

0.22

(0.01–1.01)

0.22

((0.01–1.03)

0.139

1.23

(0.46–2.69)

1.24

(0.47–2.75)

0.625

1.0

0.86

(0.51–1.42)

0.73

(0.43–1.23)

0.241

3.29

(1.54–6.37)

2.19

(1.13–4.89)

0.044

≥ 35

2.64

(0.41–10.02)

2.63

(0.40-10.27)

0.220

/

/

/

1.0

0.69

(0.34–1.48)

0.57

(0.28–1.24)

0.136

1.71

(0.88–3.58)

0.85

(0.40–1.93)

0.688

Low birth weight at full term

             

All women

1.07 (0.31–1.37)

1.14

(0.62–1.93)

0.658

0.97 (0.55–1.99)

0.98

(0.50–1.74)

0.945

1.0

1.11

(0.73–1.44)

0.97 (0.71–1.34)

0.829

1.93 (1.32–2.91)

1.34

(0.85–2.11)

0.208

Maternal age, years

             

≤ 29

1.40 (0.65–2.85)

1.30

(0.59–2.74)

0.496

1.50 (0.62–3.27)

1.55

(0.64–3.42)

0.300

1.0

1.25

(0.58–2.55)

1.20

(0.55–2.50)

0.630

8.18 (0.44–44.06)

10.42

(0.55–59.52)

0.030

30–34

0.57

(0.14–1.57)

0.61

(0.15–1.67)

0.404

0.35

(0.06–1.14)

0.37

(0.54–1.37)

0.165

1.0

0.87

(0.54–1.37)

0.77

(0.47–1.24)

0.280

1.12

(0.34–2.78)

0.89

(0.26–2.31)

0.824

≥ 35

0.96

(0.05–4.80)

0.86

(0.05–4.39)

0.888

1.48

(0.23–5.32)

1.35

(0.21–4.94)

0.697

1.0

1.18

(0.68–2.19)

1.09

(0.62–2.02)

0.784

1.80

(1.02–3.36)

1.27

(0.67–2.50)

0.478

Preterm birth

             

All women

0.99 (0.79–1.22)

0.98

(0.78–1.22)

0.867

0.83 (0.64–1.05)

0.82

(0.63–1.04)

0.113

1.0

1.27

(1.14–1.43)

1.28 (1.08–1.38)

0.001

1.74 (1.50–2.01)

1.52

(1.27–1.82)

< 0.001

Maternal age, years

             

≤ 29

0.77 (0.55–1.05)

0.90

(0.64–1.24)

0.523

0.69

(0.46-1.00)

0.75

(0.50–1.10)

0.156

1.0

1.67

(1.30–2.13)

1.50

(1.16–1.93)

0.002

1.96

(0.30–7.25)

1.34

(0.20–5.31)

0.709

30–34

1.16

(0.82–1.59)

1.19

(0.84–1.64)

0.314

0.93

(0.65–1.30)

0.96

(0.67–1.34)

0.806

1.0

1.35

(1.15–1.59)

1.21

(1.02–1.43)

0.029

2.93

(2.19–3.87)

2.17

(1.59–2.92)

< 0.001

≥ 35

1.05

(0.43–2.17)

1.01

(0.41–2.11)

0.985

0.68

(0.26–1.45)

0.65

(0.25–1.40)

0.314

1.0

1.16

(0.92–1.48)

1.06

(0.84–1.36)

0.625

1.59

(1.25–2.04)

1.17

(0.89–1.55)

0.026

Adverse neonatal Composite*

             

All women

0.68 (0.34–1.22)

0.70

(0.35–1.26)

0.265

0.70 (0.34–1.29)

0,71

(0.34–1.30)

0.300

1.0

1.19

(0.90–1.58)

1.08

(0.80–1.45)

0.631

1.33 (0.90–1.92)

0.96

(0.60–1.51)

0.852

Maternal age, years

             

≤ 29

0.38

(0.09–1.10)

0.48

(0.11–1.42)

0.237

0.74

(0.22–1.96)

0.84

(0.24–2.24)

0.753

1.0

2.17

(1.15–4.07)

1.76

(0.92–3.35)

0.085

8.18

(0.44–44.06)

4.59

(0.24–27.31)

0.165

30–34

1.14 (0.47–2.34)

1.13

(0.46–2.37)

0.758

0.90 (0.34–1.94)

0.91

(0.35–1.97)

0.827

1.0

1.17

(0.78–1.74)

1.03

(0.68–1.56)

0.873

2.41

(1.15–4.57)

1.62

(0.74–3.21)

0.194

≥ 35

0.75 0.04–3.69)

0.68

(0.04–3.41)

0.714

/

/

/

1.0

0.85

(0.51–1.50)

0.77

(0.45–1.36)

0.350

0.88 (0.49–1.62)

0.58

(0.30–1.13)

0.106

  1. aadjusted for ethnicity, maternal age at current delivery (years), educational level, residential address, pre-pregnancy BMI (kg/m2),number of miscarriages, gestational diabetes mellitus (GDM), gestational anemia, and hypertensive disorders of pregnancy; / Includes: this event was not observed in women aged ≤ 29 years and IPI ≥ 120 months; *Includes: very low birth weight, very preterm birth, severe neonatal asphyxia or and death