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Fig. 2 | BMC Ophthalmology

Fig. 2

From: Do the monocyte-derived dendritic cells exert a pivotal role in the early onset of experimental autoimmune uveitis?

Fig. 2

Distribution of moDCs in retinas of mice with EAU. (A & B) CD115 (green), CD209 (red) and both signals in superficial plexuses from central and peripheral retinas of mice with EAU at different time points with (B) or without (A) PA eye drop treatment. Arrows indicate the co-localizations of CD115 and CD209. The rightmost row is magnifications from the regions framed in yellow. (C) Statistical analysis of the co-localization of CD115- and CD209-positive areas in retina respectively between the control and treatment group (n = 4 biologically independent experiments, one-way ANOVA). (D) Schematic diagram depicting the retinal layers and the position of each vascular plexus. NFL: nerve fiber layer, GCL: ganglion cell layer, IPL: inner plexiform layer, INL: inner nuclear layer, OPL: outer plexiform layer, ONL: outer nuclear layer, RPE: retinal pigment epithelial. 200 μm and 50 μm scale bars are for photomontages and magnifications, respectively

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