Fig. 4

Changes in oral functioning burden scores over the first 2 days of treatment. Mean oral functioning burden scores at day 2 after the start of treatment were significantly better in patients who received conventional therapy plus methylene blue (MB) oral rinse at three different concentrations than in patients who received conventional therapy alone (Tukey pairwise comparison; (P = 0.0171, P = 0.0038, P = 0.0019)