Table 2 Eligibility criteria for patient participation in the Rhode Island collaborative practice agreement for naloxone (CPAN)

▪ Voluntarily request

▪ Recipient of emergency medical care for acute opioid poisoning

▪ Suspected illicit or nonmedical opioid user

▪ High dose opioid prescription (>100 morphine mg equivalents daily)

▪ Methadone prescription to opioid naïve patient

▪ Dispensed an opioid prescription and:

 ▪ History of smoking

 ▪ COPD

 ▪ Respiratory illness or obstruction

 ▪ Renal dysfunction or hepatic disease

 ▪ Known or suspected concurrent alcohol abuse

 ▪ Concurrent benzodiazepine prescription

 ▪ Concurrent SSRI or TCA anti-depressant prescription

▪ Recently released prisoners from a correctional facility

▪ Released from opioid detoxification or mandatory abstinence program

▪ Patients entering a methadone maintenance treatment program

▪ Patients that may have difficulty accessing emergency medical services