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Table 3 Univariate analysis and multivariate model of factors associated with overall survival in patients receiving curative intent therapy. HR > 1.0 indicates increased risk of death

From: Population-based analysis of curative therapies in stage II non-small cell lung cancer: the role of radiotherapy in medically inoperable patients

 

UVA

MVA

HR

p-value

HR

95% CI

p-value

Group

Surgery

Ref

< 0.001

Ref

  
 

Radiation

2.062

 

1.730

1.284–2.330

< 0.001

Age

 

1.038

< 0.001

1.013

0.998–1.029

0.094

Sex

Female

Ref

0.354

Ref

  
 

Male

1.094

 

0.979

0.757–1.267

0.873

Histology

Adenocarcinoma

Ref

 

Ref

  
 

Squamous

1.571

< 0.001

1.041

0.761–1.423

0.802

 

NOS/other

1.997

< 0.001

0.955

0.679–1.342

0.791

ECOG

0–1

Ref

< 0.001

Ref

  
 

> = 2

2.156

 

1.590

1.210–2.090

0.001

Weight loss

< 5%

Ref

 

Ref

  
 

5–10%

1.100

0.510

0.847

0.585–1.226

0.378

 

> 10%

2.294

< 0.001

1.668

1.139–2.444

0.009

 

unk

1.105

0.438

0.783

0.539–1.136

0.197

Smoking

Never

Ref

 

Ref

  
 

Former

1.391

0.126

1.097

0.595–2.020

0.767

 

Current

1.398

0.124

1.253

0.667–2.354

0.484

Chemotherapy

No

Ref

< 0.001

Ref

  
 

Yes

0.560

 

0.707

0.524–0.954

0.023

  1. UVA univariate analysis, MVA multivariate analysis, HR hazard ratio, CI confidence interval, Ref reference group
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