Fig. 1

Functional connections between lysosomes, mitochondria and MiT transcription factors. Biological mechanisms linking each organellar function with each other and with MiT transcription factors are schematically outlined. Details on study models and manipulations used to draw conclusions on the mitochondria-lysosomal connection are listed in Table 1. This figure was created using elements from Servier Medical Art, which is licensed under a Creative Commons Attribution 3.0 Unported Generic License (https://creativecommons.org/licenses/by/3.0/)