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Table 1 Biodistribution of accumulated radioactivity (SUV) in various tissues at the designed time points after administration of [18F]FEPPA

From: GMP-compliant fully automated radiosynthesis of [18F]FEPPA for PET/MRI imaging of regional brain TSPO expression

Tissues

Control

LPS (5 mg/kg)

Blood

1.29 ± 0.03

1.29 ± 0.128

Heart muscle

1.24 ± 0.06

3.60 ± 0.722*

Liver

1.48 ± 0.36

1.60 ± 0.097

Lung

1.38 ± 0.08

3.60 ± 0.722**

Spleen

1.16 ± 0.32

0.96 ± 0.443

Kidney

4.80 ± 0.57

5.86 ± 0.504

Whole brain

0.48 ± 0.05

0.76 ± 0.014

  1. Data are mean ± SEM
  2. *p < 0.05; **p < 0.01, One-way ANOVA with Bonferroni post hoc test
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