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Table 1 Baseline characteristics of study patients (matched patient pairs)

From: Selective decontamination regimens in French ICUs: association with reduced infection and resistance emergence

Variables

Standard of Care

Selective Decontamination

SMD

n = 2727

n = 2727

 

Type of ICU of admission

Polyvalent (vs surgical)—n (%)

2535 (93.0)

2522 (92.5)

0.02

Workload in ICU of admission, number of admissions per bed per year

28.85 [25.56–36.97]

32.60 [26.50–33.25]

0.05

Hydro-alcoholic solution consumption in ICU of admission, L per patient-day

0.15 [0.14–0.20]

0.16 [0.13–0.18]

0.05

Age, year

65.60 [53.95–74.20]

63.30 [51.20–71.90]

0.09

Male—n (%)

1859 (68.2)

1862 (68.3)

0.00

Immunocompromised

  

0.04

 Neutropenia < 500 G/L—n (%)

124 (4.5)

141 (5.2)

0.04

 Others—n (%)

212 (7.8)

182 (6.7)

0.16

 None—n (%)

2391 (87.7)

2404 (88.2)

0.07

SAPS II

54 [41–67]

54 [40–68]

0.03

Year of admission

   

 2018—n (%)

282 (10.3)

437 (16.0)

0.15

 2019—n (%)

343 (12.6)

360 (13.2)

0.02

 2020—n (%)

222 (8.1)

285 (10.5)

0.07

 2021—n (%)

756 (27.7)

570 (20.9)

0.17

 2022—n (%)

1124 (41.2)

1075 (39.4)

0.04

Localization before admission

   

 Home—n (%)

1692 (62.0)

1768 (64.8)

0.06

 Acute care ward—n (%)

912 (33.4)

830 (30.4)

0.07

 Other ICU—n (%)

123 (4.5)

129 (4.7)

0.01

Type of admission

   

 Planned surgery—n (%)

152 (5.6)

149 (5.5)

0.00

 Urgent surgery—n (%)

873 (32.0)

932 (34.2)

0.04

 Medicine—n (%)

1702 (62.4)

1646 (60.4)

0.04

Trauma—n (%)

598 (21.9)

690 (25.3)

0.08

COVID-19—n (%)

313 (11.5)

264 (9.7)

0.06

Early management

   

 Therapeutic antibiotics—n (%)

1411 (51.7)

1409 (51.7)

0.00

 Central venous catheter—n (%)

2483 (91.1)

2490 (91.3)

0.01

  1. Categorical variables are expressed as percentages and continuous variables as median and interquartile range
  2. ICU Intensive-care unit, COVID-19 SARS-COV 2 associated infection disease, SMD standardized mean difference