Abstract
Whether early pet-keeping is a risk factor for children’s asthma and allergies remains controversial. To investigate associations between asthma, allergies and airway symptoms among children and the indoor environment, a cross-sectional study was conducted in 5 districts of Shanghai. A number of 13335 questionnaires (response rate: 85.3%) of 4-6 year old children were analyzed. Families in urban areas have more pets except for dogs than families in suburbs. Fish are the most common pets in urban districts. The prevalence of doctor-diagnosed asthma was 10.3%, wheeze (ever) 28.3%, rhinitis (ever) 54.1%, doctor-diagnosed hay fever 12.6% and eczema (ever) 22.9%. In logistic regression analyses, early furred pet-keeping was positively associated with most of the symptoms and significantly with rhinitis (ever, adjusted OR=1.41, 95% CI=1.14–1.76) and doctor-diagnosed hay fever (1.38, 1.02–1.88). Current furred pet-keeping was significantly negatively associated with doctor-diagnosed asthma (0.57, 0.39–0.83). Persistent furred pet-keeping was significantly positively associated with rhinitis on pet or pollen exposure. However, current pet-keeping is not randomly distributed in the population. Children in families with “allergy” or with “pet avoidance behavior” (due to allergies in the family) have more symptoms, but have avoided cats and dogs, leading to the conclusion that such animals are “protective”, namely the “Healthy Pet-Keeping” effect. Moreover, rodents and birds are risks for children’s health. Fish-keeping is also seemingly a risk. This study indicates that early pet-keeping is a risk factor for asthma and allergies in families with a history of allergies, and part of residents in Shanghai have pet-avoidance behavior.
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References
Ahlbom A, Backman A, Bakke J, et al. “NORDPET”—A risk factor for or protection against sensitization/allergy: A Nordic interdisciplinary review of the scientific literature concerning the relationship between the exposure to pets at home, sensitization and the development of allergy. Indoor Air, 1998, 8: 219–235
Apelberg B J, Aoki Y, Jaakkola J J K. Systematic review: Exposure to pets and risk of asthma and asthma-like symptoms. J Allergy Clin Immunol, 2001, 107: 455–460
Chen C M, Tischer C, Schnappinger M, et al. The role of cats and dogs in asthma and allergy—A systematic review. Int J Hyg Environ Health, 2010, 213: 1–31
Lodge C J, Allen K J, Lowe A J, et al. Perinatal cat and dog exposure and the risk of asthma and allergy in the urban environment: A systematic review of longitudinal studies. Clin Dev Immunol, 2012, doi: 10.1155/2012/176484
Takkouche B, González-Barcala F J, Etminan M, et al. Exposure to furry pets and the risk of asthma and allergic rhinitis: A meta-analysis. Allergy, 2008, 63: 857–864
Matheson M C, Dharmage S C, Abramson M J, et al. Early-life risk factors and incidence of rhinitis: Results from the European Community Respiratory Health Study—An international population-based cohort study. J Allergy Clin Immunol, 2011, 128: 816–823
Celedón J C, Litonjua A A, Ryan L, et al. Exposure to cat allergen, maternal history of asthma, and wheezing in first 5 years of life. Lancet, 2002, 360: 781–782
Solo P, Xia J, Johnson C A, et al. Indoor allergens, asthma, and asthma-related symptoms among adolescents in Wuhan, China. Ann Epidemiol, 2004, 14: 543–550
Lodge C J, Lowe A J, Gurrin L C, et al. Pets at birth do not increase allergic disease in at-risk children. Clin Exp Allergy, 2012, 42: 1377–1385
Nafstad P, Magnus P, Gaarder P I, et al. Exposure to pets and atopy-related diseases in the first 4 years of life. Allergy, 2001, 56: 307–312
Ownby D R, Johnson C C, Peterson E L. Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA, 2002, 288: 963–972
Perzanowski M S, Rönmark E, Platts-Mills T A E, et al. Effect of cat and dog ownership on sensitization and development of asthma among preteen age children. Am J Respir Crit Care Med, 2002, 166: 696–702
Oberle D, Mutius E, Kries R. Childhood asthma and continuous exposure to cats since the first year of life with cats allowed in the child’s bedroom. Allergy, 2003, 58: 1033–1036
Mandhane P J, Sears M R, Poulton R, et al. Cats and dogs and the risk of atopy in childhood and adulthood. J Allergy Clin Immunol, 2009, 124: 745–750
Gaffin J M, Spergel J M, Boguniewicz M, et al. Effect of cat and daycare exposures on the risk of asthma in children with atopic dermatitis. Allergy Asthma Proc, 2012, 33: 282–288
Anyo G, Brunekreef B, Meer G, et al. Early, current and past pet ownership: Associations with sensitization, bronchial responsiveness and allergic symptoms in school children. Clin Exp Allergy, 2002, 32: 361–366
Bornehag C G, Sundell J, Hagerhed L. Pet-keeping in early childhood and airway, nose and skin symptoms later in life. Allergy, 2003, 58: 939–944
Naydenov K, Popov T, Mustakov T, et al. The association of pet keeping at home with symptoms in airways, nose and skin among Bulgarian children. Pediatr Allergy Immunol, 2008, 19: 702–708
Dong G H, Ma Y N, Ding H L, et al. Pets keeping in home, parental atopy, asthma, and asthma-related symptoms in 12910 elementary school children from northeast China. Indoor Air, 2009, 19: 166–173
Lombardi E, Simoni M, Grutta S L. Effects of pet exposure in the first year of life on respiratory and allergies in 7-yr-old children. The SIDRIA-2 study. Pediatr Allergy Immunol, 2010, 21: 268–276
Chen Y C, Tsaia C H, Leo Lee Y L. Early-life indoor environmental exposures increase the risk of childhood asthma. Int J Hyg Environ Health, 2011, 215: 19–25
Brunekreef B, Mutius E V, Wong G, et al. Exposure to cats and dogs, and symptoms of asthma, rhinoconjunctivitis, and eczema. Epidemiology, 2012, 23: 742–750
Bertelsen R J, Carlsen K C L, Granum B, et al. Do allergic families avoid keeping furry pets? Indoor Air, 2010, 20: 187–195
Sun Y X, Sundell J. Life style and home environment are associated with racial disparities of asthma and allergy in Northeast Texas children. Sci Total Environ, 2011, 409: 4229–4234
Zheng T Z, Niu S R, Lu B Y, et al. Childhood asthma in Beijing, China: A population-based case-control study. Am J Epidemiol, 2002, 156: 977–983
Wang S L, Guo X B, Zhang J L. Study on the effects of ambient air pollution on respiratory disease and symptoms among school-age children in Beijing (in Chinese). J Environ Health, 2004, 21: 41–44
Zheng Q, Guo Y. Impact of indoor environmental factors on bronchial asthma (in Chinese). Chin J Asthma, 2011, 5: 138–143
Dong W, Sheng J, Gu X M, et al. Allergens and their relationships to childhood bronchial asthma in the Jiading District of Shanghai (in Chinese). Chin J Contemp Pediatr, 2012, 14: 521–523
Asher M I, Keil U, Anderson H R, et al. International study of asthma and allergies in childhood (ISAAC): Rationale and methods. Eur Respir J, 1995, 8: 483–491
Engman L H. Indoor environmental factors and its associations with asthma and allergy among Swedish pre-school children. Doctoral Dissertation. Lund: Lund University, 2006
Naydenov K G. On the association between home exposure and asthma and allergies among children in Bulgaria /The ALLHOME Study/. Doctoral Dissertation. Lyngby: Technical University of Denmark and ICIEE, 2007
Zuraimi M S. Child care centre and home exposures among preschool children in Singapore and their associations with asthma, allergies and respiratory symptoms. Doctoral Dissertation. Singapore: National University of Singapore, 2008
Asher M I, Montefort S, Bjökstén B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet, 2006, 368: 733–743
Yuan D, Shen C L, Jiang Z H, et al. An investigation on the prevalence of asthma and its influence factors among school age children in Shanghai (in Chinese). J Environ Occup Med, 2007, 24: 573–576
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Huang, C., Hu, Y., Liu, W. et al. Pet-keeping and its impact on asthma and allergies among preschool children in Shanghai, China. Chin. Sci. Bull. 58, 4203–4210 (2013). https://doi.org/10.1007/s11434-013-5679-4
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DOI: https://doi.org/10.1007/s11434-013-5679-4