Abstract
Gold nanoparticles with different morphologies, such as spindle, octahedron, and decahedron were obtained by using different molar ratios of HAuCl4/HEPES in the presence and absence of surfactants at room temperature. These nanoparticles were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM), scanning electron microcopy (SEM), energy-dispersive X-rays analysis (EDX), and selected area electron diffraction (SAED). The kinetics of the formation of gold nanoparticles in HEPES buffer was studied by UV-visible spectrophotometer. The formation of gold nanoparticles was strongly dependent on the concentration of HEPES and pH value. The surfactants play a crucial role in the size and shape controlled synthesis of gold nanoparticles.
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Shipway A.N., Katz A., and Willner I., Nanoparticle arrays on surfaces for electronic, optical, and sensor applications, Chem. Phys. Chem., 2000, 1(1): 18.
Sun R.W.Y., Chen R., Chung N.P.Y., Ho C.M., Lin C.L.S., and Che C.M., Silver nanoparticles fabricated in Hepes buffer exhibit cytoprotective activities toward HIV-1 infected cells, Chem. Commun., 2005, 40: 5059.
Milliron D.J., Hughes S.M., Cui Y., Manna L., Li J., Wang L.W., and Alivisatos A.P., Colloidal nanocrystal heterostructures with linear and branched topology, Nature, 2004, 430: 190.
Liz-Marzán L.M., Tailoring surface plasmons through the morphology and assembly of metal nanoparticles, Langmuir, 2006, 22(1): 32.
Lok C.N., Ho C.M., Chen R., He Q.Y., Yu W.Y., Sun H., Tam P.K.H., Chiu J.F., and Che C.M., Silver nanoparticles: partial oxidation and antibacterial activities, J. Biol. Inorg. Chem., 2007, 12: 527.
Elghanian R., Storhoff J.J., Mucic R.C., Letsinger R.L., and Mirkin C.A., Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles, Science, 1997, 277: 1078.
Chan W.C.W. and Nie S., Quantum dot bioconjugates for ultrasensitive nonisotopic detection, Science, 1998, 281: 2016.
Han M., Gao X., Su J.Z., and Nie S., Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules, Nat. Biotechnol., 2001, 19: 631.
Mirkin C.A., Letsinger R.L., Mucic R.C., and Storhoff J.J., A DNA-based method for rationally assembling nanoparticles into macroscopic materials, Nature, 1996, 382: 607.
Schultz S., Smith D.R., Mock J.J., and Schultz D.A., Single-target molecule detection with nonbleaching multicolor optical immunolabels, Proc. Natl. Acad. Sci. USA, 2000, 97(3): 996.
Bruchez Jr M., Moronne M., Gin P., Weiss S., and Alivisatos A.P., Semiconductor nanocrystals as fluorescent biological labels, Science, 1998, 281: 2013.
Liu T., Tang J., and Jiang L., The enhancement effect of gold nanoparticles as a surface modifier on DNA sensor sensitivity, Biochem. Biophys. Res. Commun., 2004, 313(1): 3.
Tshikhudo T.R., Demuru D., Wang Z., Brust M., Secchi A., Arduini A., and Pochini A., Molecular recognition by calix[4]arene-modified gold nanoparticles in aqueous solution, Angew. Chem. Int. Ed., 2005, 44(19): 2917.
Huang D., Liao F., Molesa S., Redinger D., and Subramanian V., Plastic-compatible low resistance printable gold nanoparticle conductors for flexible electronics, J. Electrochem. Soc., 2003, 150(7): 412.
Niemeyer C.M. and Dr P.D., Nanoparticles, proteins, and nucleic acids: biotechnology meets materials science, Angew. Chem. Int. Ed., 2001, 40(22): 4128.
Hill H.D., Macfarlane R.J., Senesi A.J., Lee B., Park S.Y., and Mirkin C.A., Controlling the lattice parameters of gold nanoparticle FCC crystals with duplex DNA linkers, Nano Lett., 2008, 8(8): 2341.
Tabata M., Habib A. and Watanabe K., DNA cleavage by good’s buffers in the presence of Au(III), Bull. Chem. Soc. Jpn., 2005, 78: 1263.
Nicewarner-Peña S.R., Raina S., Goodrich G.P., Fedoroff N.V., and Keating C.D., Hybridization and enzymatic extension of Au nanoparticle-bound oligonucleotides, J. Am. Chem. Soc., 2002, 124(25): 7314.
Tkachenko A.G., Xie H., Coleman D., Glomm W., Ryan J., Anderson M.F., Franzen S., and Feldheim D.L., Multifunctional gold nanoparticle-peptide complexes for nuclear targeting, J. Am. Chem. Soc., 2003, 125(16): 4700.
Dragnea B., Chen C., Kwak E.S., Stein B., and Kao C.C., Gold nanoparticles as spectroscopic enhancers for in vitro studies on single viruses, J. Am. Chem. Soc., 2003, 125(21): 6374.
Bowman M.G., Ballard T.E., Ackerson C.J., Feldheim D.L., Margolis D.M., and Melander C., Inhibition of HIV fusion with multivalent gold nanoparticles, J. Am. Chem. Soc. 2008, 130(22): 6896.
Schmid G. and Corain B., Nanoparticulated gold: syntheses, structures, electronics, and reactivities, Eur. J. Inorg. Chem., 2003, (17): 3081.
García-Serrano J., Pal U., Herrera A.M., Salas P., and Ángeles-Chávez C., One-step “green” synthesis and stabilization of Au and Ag nanoparticles using ionic polymers, Chem. Mater., 2008, 20(16): 5146.
Link S., Wang Z.L., and EI-Sayed M.A., Alloy formation of gold-silver nanoparticles and the dependence of the plasmon absorption on their composition, J. Phys. Chem. B, 1999, 103(18): 3529.
Okitsu K., Yue A., Tanabe S., Matsumoto H., and Yobiko Y., Formation of colloidal gold nanoparticles in an ultrasonic field: control of rate of gold (III) reduction and size of formed gold particles, Langmuir, 2001, 17(25): 7717.
Mukhejee P., Ahmad A., Mandal D., Senapati S., Sainkar S.R., Khan M.I., Ramani R., Parischa R., Ajayakumar P.V., Alam M., Sastry M., and Kumar R., Bioreduction of 4 AuCl −4 ions by the fungus, Verticillium sp. and surface trapping of the gold nanoparticles formed, Angew. Chem. Int. Ed., 2001, 40(19): 3585.
Sugunan A., Melin P., Schnürer J., Hilborn J.G., and Dutta J., Nutrition-driven assembly of colloidal nanoparticles: growing fungi assemble gold nanoparticles as microwires, Adv. Mater., 2007, 19(1): 77.
He S., Guo Z., Zhang Y., Zhang S., Wang J., and Gu N., Biosynthesis of gold nanoparticles using the bacteria Rhodop-seudomonas capsulata, Mater. Lett., 2007, 61(18): 3984.
Habib A., Tabata M., and Wu Y.G., Formation of gold nanoparticles by Good’s buffers, Bull. Chem. Soc. Jpn., 2005, 78: 262.
Xie J., Lee J.Y., and Wang D.I.C., Seedless, surfactantless, high-yield synthesis of branched gold nanocrystals in HEPES buffer solution, Chem. Mater., 2007, 19(11): 2823.
Jena B.K. and Raj C.R., Synthesis of flower-like gold nanoparticles and their electrocatalytic activity towards the oxidation of methanol and the reduction of oxygen, Langmuir, 2007, 23(7): 4064.
Grady J.K., Chasteen N.D., and Harres D.C., Radicals from Good’s buffers, Anal. Biochem., 1988, 173(1): 111.
Hegetschweiler K. and Saltman P., Interaction of copper(II) with N-(2-hydroxyethyl)piperazine-N′-ethanesulfonic acid (HEPES), Inorg. Chem., 1986, 25(1): 107.
Wu S.H. and Chen D.H., Synthesis of high-concentration Cu nanoparticles in aqueous CTAB solutions, J. Colloid Interface Sci., 2004, 273(1): 165.
Wiley B., Sun Y., Mayers B., and Xia Y., Shape-controlled synthesis of metal nanostructures: the case of silver, Chem. Eur. J., 2004, 11(2): 454.
Cao C., Park S., and Sim S.J., Seedless synthesis of octahedral gold nanoparticles in condensed surfactant phase, J. Colloid Interface Sci., 2008, 322(1): 152.
Robertson D., Tiersch B., Kosmella S., and Koetz J., Preparation of crystalline gold nanoparticles at the surface of mixed phosphatidylcholine-ionic surfactant vesicles, J. Colloid Interface Sci., 2007, 305(2): 345.
Mandal S., Arumugam S.K., Adyanthaya S.D., Pasricha R., and Sastry M., Use of aqueous foams for the synthesis of gold nanoparticles of variable morphology, J. Mater. Chem. 2004, 14: 43.
Sun Y. and Xia Y., Shape-controlled synthesis of gold and silver nanoparticles, Science, 2002, 298: 2176.
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Chen, R., Wu, J., Li, H. et al. Fabrication of gold nanoparticles with different morphologies in HEPES buffer. Rare Metals 29, 180–186 (2010). https://doi.org/10.1007/s12598-010-0031-5
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DOI: https://doi.org/10.1007/s12598-010-0031-5