Abstract
Hydrophilic polymer coatings can improve the surface characteristics of artificial implants. However, because they are used in vivo, they inevitably come into contact with biomolecules that affect their interfacial tribological properties. In this paper, the friction behaviors of poly(vinylphosphonic acid) (PVPA)-modified Ti6Al4V and polytetrafluorethylene balls were analyzed using albumin, globulin, aggrecan, and hyaluronic acid as lubricants. The interaction properties and dynamic adsorption characteristics of the biomolecules and PVPA molecules were explored by a quartz crystal microbalance to identify the cause of the friction difference. It was found that protein molecules disturbed the superlubricity of the PVPA-phosphate-buffered saline system because of the formation of a stable adsorption film, which replaced the interfacial characteristics of the PVPA coating. Polysaccharides, with their excellent hydration properties and polymer structure, had an unstable dynamic interaction or zero adsorption with PVPA molecules, and hardly changed the superlubricity of the PVPA and phosphate-buffered-saline system. The influence mechanism of the specific friction of proteins and polysaccharides was analyzed. Interactions were observed among different biomolecules. Polysaccharides can potentially reduce protein adsorption. The result of the synergistic regulation of the friction coefficient for PVPA-modified Ti6Al4V is approximately 0.017. The results of this study will provide a theoretical basis for the use of polymer coatings in vivo.
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Acknowledgements
This work was supported by the National Natural Science Foundation of China (51705010, 51875303), the Beijing Natural Science Foundation (3192003), the General Project of Science and Technology Plan from Beijing Educational Committee (KM201810005013), the Tribology Science Fund of State Key Laboratory of Tribology (STLEKF16A02, SKLTKF19B08), the training program of Rixin talent and outstanding talent from Beijing University of Technology.
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Caixia ZHANG. She received her Ph.D. degree in mechanical engineering in 2015 from Tsinghua University, Beijing, China. After then, she joined the Beijing Key Laboratory of Advanced Manufacturing Technology, Beijing University of Technology. Her research interests include biotribology, superlubricity, and surface and interface analysis.
Junmin CHEN. He received his bachelor degree from Luoyang Institute of Science and Technology, China, in 2019. He is currently a graduate student at the Institute of Advanced Manufacturing and Intelligent Technology, Beijing University of Technology, China. His research interests include biotribology, superlubricity, surface and interface analysis, and triboelectric nanogenerator.
Mengmeng LIU. She received her bachelor degree from Applied Technology College of Soochow University, China. She is currently a graduate student at the Beijing University of Technology, China. Her research interests include superlubricity and the control of the smart surface and interface.
Yuhong LIU. She received her Ph. D. degree in CAS Key Laboratory of Molecular Nanostructure & Nanotechnology Institute of Chemistry, Chinese Academy of Sciences, Beijing, China in 2005. She joined the State Key Laboratory of Tribology at Tsinghua University in 2005. Her current position is as an associate professor. Her research areas cover nanotribology, nanostructure & nanotechnology of surface and interface, chemical-mechanical planarization, and water-based lubrication.
Zhifeng LIU. He received his Ph.D. degree in mechanical engineering from Northeastern University, Shenyang, China. He is the team leader of the Institute of Advanced Manufacturing and Intelligent Technology, Beijing University of Technology. His research interests include heavy-duty machine tools, superlubricity, robot, and assembly technology.
Hongyan CHU. She received her Ph.D. degree in mechanical design and theory in 2003 from the Beijing University of Technology. And now she works at the Institute of Advanced Manufacturing and Intelligent Technology, Beijing University of Technology. Her research interests include intelligent manufacturing technology, surface and friction characteristics, and contact dynamics of viscoelastic material.
Qiang CHENG. He is a professor of the Institute of Advanced Manufacturing and Intelligent Technology, Beijing University of Technology. He received his Ph.D. degree in mechanical engineering in 2009 from Huazhong University of Science and Technology, Wuhan, China. His main research interests include wear modeling and validation, interface engineering, and precision retaining ability design.
Jianhua WANG. She graduated from Tsinghua University, Beijing, China. After then, she joined the Beijing University of Technology. Her research interests include precision machine tools, smart surface, and interface.
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Zhang, C., Chen, J., Liu, M. et al. Regulation mechanism of biomolecule interaction behaviors on the superlubricity of hydrophilic polymer coatings. Friction 10, 94–109 (2022). https://doi.org/10.1007/s40544-020-0441-9
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DOI: https://doi.org/10.1007/s40544-020-0441-9