Abstract
Trait aggression can lead to catastrophic consequences for individuals and society. However, it remains unclear how aggressive people differ from others regarding basic, task-independent brain characteristics. We used EEG microstate analysis to investigate how the temporal organization of neural resting networks might help explain inter-individual differences in aggression. Microstates represent whole-brain networks, which are stable for short timeframes (40–120 ms) before quickly transitioning into other microstate types. Recent research demonstrates that the general temporal stability of microstates across types predicts higher levels of self-control and inhibitory control, and lower levels of risk-taking preferences. Given that these outcomes are inversely related to aggression, we investigated whether microstate stability at rest would predict lower levels of trait aggression. As males show higher levels of aggression than females, and males and females express aggression differently, we also tested for possible gender-differences. As hypothesized, people with higher levels of trait aggression showed lower microstate stability. This effect was moderated by gender, with men showing stronger associations compared to women. These findings support the notion that temporal dynamics of sub-second resting networks predict complex human traits. Furthermore, they provide initial indications of gender-differences in the functional significance of EEG microstates.
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Introduction
Aggression is widely regarded as a maladaptive trait in modern societies, as it leads to negative consequences for both victims and aggressors. For example, trait aggression predicts domestic violence (Ruddle et al. 2017), aggression in the workplace (Douglas and Martinko 2001), and aggressive driving behavior (Deffenbacher et al. 2001). On the other hand, trait aggression is associated with adverse outcomes for aggressors, including social exclusion (Twenge et al. 2001), mental health issues (Blair 2001; Twenge and Campbell 2003), and imprisonment (Falk et al. 2017). Interestingly, there are large inter-individual differences in trait aggression (for reviews, see Wilkowski and Robinson 2008; DeWall et al. 2011a), with only a small percentage of the population accounting for the majority of violent acts (Falk et al. 2014). Although aggression has been extensively studied on social (e.g., Bandura 1973; Berkowitz 1993), psychological (e.g., Anderson and Bushman 2002), and neuroscientific (e.g., Nelson and Trainor 2007) levels, it remains unclear if and how aggressive people differ from others in regard to fundamental, task-independent, brain characteristics.
Here, we follow a neural trait approach to examine how basic neural processing at rest may help explain the sources of individual levels of aggression. The neural trait approach involves measuring stable characteristics in resting-state brain recordings and investigating whether these characteristics are associated with cognitive, biological, and behavioral processes (e.g., Schiller et al. 2014, 2020a, b, 2021; Leota et al. 2021; Nash et al. 2022; Kleinert et al. 2022). This task-independent approach compliments existing, task-dependent analyses of neural and psychological processes (for more on the benefits of task-independence, see Berkman and Falk 2013). Perhaps most importantly for individual difference research, neural traits are objective—unadulterated by personal biases and demand characteristics.
Research examining resting-state electroencephalography (EEG) has demonstrated that neural network activation remains stable for approximately 40–120 ms before quickly transitioning into another network type. These “basic building blocks of cognition” (Lehmann et al. 1998) are called microstates (for reviews, see Khanna et al. 2015; Michel and Koenig 2018). During spontaneous neural processing at rest, only four microstate types (A, B, C and D) typically explain 70 to 80% of variance in individual EEGs (Koenig et al. 2002). All four types represent widely distributed networks, which share common neural generators including the anterior cingulate cortex (ACC), the insula, and parts of the parietal and prefrontal cortices (Custo et al. 2017; Milz et al. 2017), and resemble fMRI resting networks (Britz et al. 2010; Musso et al. 2010; Yuan et al. 2012; Abreu et al. 2021). Moreover, durations and occurrences of the four different microstate types are highly correlated (average correlation of durations: r = 0.79; average correlation of occurrences: r = 0.51; Khanna et al. 2014), supporting the notion that the general microstate stability represents a neural trait that overarches characteristics of specific microstate types. Interestingly, there is a high degree of heterogeneity in microstate stability at rest, across all microstate types (Koenig et al. 2002; Schiller et al. 2020b; Kleinert et al. 2022). Thus, some people show substantially higher microstate stability (e.g., an average duration of 120 ms and 8 occurrences per second) than others (e.g., an average duration of 40 ms and 25 occurrences per second). Although research on EEG microstates has increased exponentially in recent years (e.g., da Cruz et al. 2020; de Bock et al. 2020; Schiller et al. 2020a, b; Zanesco et al. 2020; Abreu et al. 2021; Pal et al. 2021; Poskanzer et al. 2021; Kleinert et al. 2022), most studies focused on abnormal microstate characteristics of specific microstate types in clinical populations (for an overview, see Michel and Koenig 2018). Currently, little is known about the functional significance of microstate stability in healthy populations. Here, we examined the hypothesis that the temporal stability of microstates (as indicated by longer durations and fewer occurrences of networks) is positively associated with individual levels of trait aggression, based on the following considerations.
First, resting-state microstate characteristics are prime candidates for neural trait research, which have been associated with the Big 5 personality traits (Zanesco et al. 2020), paranormal belief (Schlegel et al. 2012) and prosocial behavioral preferences (Schiller et al. 2020b). Individual microstate dynamics can be interpreted as “neural signatures” because individuals evidence distinct microstate sequences (Van de Ville et al. 2010) and microstate characteristics are highly reliable (Khanna et al. 2014; Liu et al. 2020; Schiller et al. 2020b) and heritable (da Cruz et al. 2020). Second, common neural sources of resting-state microstates correspond to neural sources of aggression, including the anterior cingulate cortex, the insula, and parts of the prefrontal cortex (Denson et al. 2009; Chester et al. 2014; Dambacher et al. 2015; Repple et al. 2017; Skibsted et al. 2017), brain regions also involved in the regulation of self- and inhibitory control (MacDonald et al. 2000; Allman et al. 2001; Figner et al. 2010; Menon and Uddin 2010). Thus, more effective functioning of these brain regions at rest might contribute to both higher microstate stability as well as increased control over aggressive impulses. Third, a recent study investigated general microstate stability and demonstrated positive associations with trait self-control and a neural index of inhibitory control, and a negative association with risk-taking behavior (Kleinert et al. 2022). As aggression is associated with lower levels of self-control (for reviews, see Baumeister and Boden 1998; Denson et al. 2012; DeWall et al. 2011b), lower levels of inhibitory control (Stucke and Baumeister 2006; Raaijmakers et al. 2008; Pawliczek et al. 2013) and higher levels of risk-taking behavior (for a review, see Kuin et al. 2015), higher microstate stability might indicate lower levels of trait aggression.
To date, only a very few studies have considered possible gender-differences in resting-state microstates (Tomescu et al. 2018; Zanesco et al. 2020). In fact, the majority of studies were based on exclusively male samples (for an overview of studies, see Michel and Koenig 2018). On the other hand, aggression shows large gender-differences (Zell et al. 2015). Factors that contribute to higher levels of aggression in men compared to women include evolutionary adaptation (for reviews, see Campbell 1999; Puts 2016), testosterone availability (for a review, see Archer 2006; for a meta-analysis, see Book et al. 2001), differences in brain-structures (for a review, see Archer 2019), and socialization (Moore and Stuart 2004; Cohn and Zeichner 2006). Furthermore, previous studies found gender-differences in how different facets of aggression are expressed, with females using more indirect/relational aggressive strategies, and males using more direct/physical forms of aggression (Lagerspetz et al. 1988; Cairns et al. 1989; Buss and Perry 1992; Crick and Grotpeter 1995). Based on these findings, we also investigated possible gender-differences in the associations between microstate stability and trait aggression and its facets (i.e., physical aggression, verbal aggression, hostility and anger; Buss and Perry 1992).
Materials and Methods
Participants
A total sample of 110 healthy students from Canada (right-handed, native speakers or fluent in English, normal or corrected-to-normal vision and hearing) was recruited for this study. Nine participants were excluded because of bad EEG quality, resulting in a final sample size of N = 101 for all statistical analyses (58 women and 43 men; mean age = 19.76 years, range 17–26). Based on an estimated medium effect size of b = 0.27 in similar research (Kleinert et al. 2022), an a priori power analysis in G*Power (α = 0.05, power = 0.85; Faul et al. 2009) resulted in a required sample size of 93 participants. Participants showed normal emotional stability (as measured by the Ten Item Personality Inventory; Gosling et al., 2003) compared to norm values (Gosling et al., 2014; men: M = 4.75, SD = 0.941; norm values: M = 4.61, SD = 1.47; women: M = 3.99, SD = 1.32; norm values: M = 4.07, SD = 1.46). The study was carried out according to the principles of the Declaration of Helsinki. It was approved by the local university’s ethics committee, and all participants provided informed written consent.
Procedure
First, participants were seated in an electrically- and noise-shielded cabin, where they were equipped with a 64-electrode EEG system (Brain Products GmbH, Munich, Germany). Next, participants provided demographic information and completed the Aggression Questionnaire along with other scales that are not part of the current study. All materials were in English. Then, we recorded four minutes of resting-state EEG (60 s eyes-open, 60 s eyes-closed, two runs). Alternating eyes-open and eyes-closed periods were used to avoid fatigue in participants and thus achieve more stable EEG recordings (Barry et al. 2007; Schiller et al. 2014, 2019, 2020b; Baumgartner et al. 2019). In line with standard procedures (Damoiseaux et al. 2006; Mantini et al. 2007; for reviews, see Lee et al. 2013; Newson and Thiagarajan 2019), only eyes-closed periods were used for further analyses (max. duration: 120 s). Next, participants completed several computerized tasks that are evaluated elsewhere (Nash et al. 2020, 2021; Kleinert et al. 2022). Note that this study is based on the same data, but uniquely focuses on associations of microstate stability with aggression that have not been previously reported. Finally, participants were compensated for participation with class-credit. All data and code needed to reproduce the results of this work are available in the supplementary material.
Measurement of Aggression
Participants completed the brief version of the Aggression Questionnaire (AQ; Buss and Perry 1992; Bryant and Smith 2001). The original scale shows good internal consistency (α = 0.89) and retest reliability (r = 0.80; Buss and Perry 1992), differentiates between participants with higher and lower aggressive behavior (Harris 1997), and is associated with other scales of aggression (Buss and Perry 1992; Harris 1997). The main advantage of the brief version is the superior goodness of fit index of the measurement model (GFI = 0.94) compared to the original scale (GFI = 0.76–0.81). The brief version consists of 12 items, which were rated on 6-point Likert scales ranging from 1 (“not at all characteristic of me”) to 6 (“very much characteristic of me”). It includes the four subscales physical aggression (e.g., “Given enough provocation, I may hit another person”; α = 0.72), verbal aggression (e.g., “My friends say that I’m somewhat argumentative”; α = 0.78), hostility (e.g., “Other people always seem to get the breaks”; α = 0.75) and anger (e.g., “I have trouble controlling my temper”; α = 0.70), which are measured by three items each. Final aggression scores are calculated as the mean of all 12 items (or the mean of the three respective items for subscales), with higher scores indicating more aggression.
EEG Recording and Preprocessing
We used a 64-electrode EEG system with Ag/AgCI electrodes for electrophysiological recordings of resting-state brain activity (ActiCHamp; Brain Products GmbH, Munich, Germany). Electrodes were positioned according to the 10/10 montage (reference electrode: TP9), and EEG measures were recorded with a sampling-rate of 512 Hz and an online band-pass filter between 0.1 and 100 Hz. Preprocessing of raw EEG data was conducted in the BrainVision Analyzer (version 2.1.0.327; Brain Products GmbH, Munich, Germany). First, we applied a band-pass filter from 1.5 to 20 Hz and a notch filter of 60 Hz to remove any remaining power-line artifacts. Eye movement artifacts were removed using an independent component analysis (ICA). We interpolated channels that were inactive or heavily affected by artifacts (based on expert manual inspections) using neighboring channels. No channels were interpolated in 84 out of 101 participants (83%). On average, 0.267 channels were interpolated (range 0–6). To eliminate any remaining artifacts, we used a semi-automatic artifact-rejection. First, we applied an automatic rejection procedure, in which amplitudes higher than 100 μV or lower than − 100 μV were defined as artifacts. This procedure was followed by an expert manual inspection of the data to reject any remaining artifacts that were not captured by the automatic procedure. Then, EEGs were segmented into eyes-open and eyes-closed periods. Finally, signals were re-derived to average reference and segmented into epochs of two seconds for microstate analysis (eyes-closed periods only).
EEG Microstate Analysis
A plugin for resting-state microstate analysis by Koenig (2017) was used to quantify individual levels of microstate stability in EEGLAB (Delorme and Makeig 2004). The plugin follows standard procedures (Lehmann et al. 1987; Strik and Lehmann 1993; Wackermann et al. 1993). First, artifact-free, eyes-closed EEG signals from all 64 electrodes were used to extract electric potential field maps at timepoints of maximum global field power (GFP). Only using maps from GFP-peaks results in an optimal signal-to-noise ratio (Koenig et al. 2002). Second, the four most predominant individual microstate-maps were identified using an atomize-agglomerate hierarchical clustering procedure (AAHC; Murray et al. 2008; Michel et al. 2009). Third, individual maps were submitted to another cluster analysis yielding grand-mean microstate maps across subjects, which were sorted to follow the standard order of A, B, C, D (Koenig et al. 2002). Note that the four grand-mean microstate maps closely resemble the four prototypical resting-state microstate types (see Table 1; for reviews, see Khanna et al. 2015; Michel and Koenig 2018). Fourth, mean microstate maps of each subject were assigned to one of the four prototypical microstate types based on spatial correlations with grand-mean maps. Fifth, continuous sequences of microstate maps were obtained by assigning each subject’s electric potential field maps (see step 1) to the best fitting mean microstate map. These individual sequences were used to obtain average durations of all four microstate types in milliseconds (duration A–D) and the average number of occurrences of all four microstate types per second (occurrence A–D). Mean duration refers to the average duration across all four microstate types A–D, and mean occurrence refers to the average number of occurrences of all four microstate types A–D per second. Note that mean duration and mean occurrence are negatively related to each other, as longer durations naturally predict fewer occurrences of microstates. Therefore, we use the term microstate stability to describe the overall, microstate type-independent tendency of individuals to show longer durations and fewer occurrences of resting-state microstates.
Statistical Analysis
We first investigated the overall tendency of individuals for higher or lower microstate stability by comparing a basic model of microstate duration (and microstate occurrence) across microstate types (data in long format) with a mixed model of microstate duration (and microstate occurrence) including a random intercept across participants (also see Kleinert et al. 2022). If the models including a random intercept would show significantly higher model fits, this would confirm substantial intercorrelations of durations (and occurrences) within individuals. Additionally, we analyzed effect sizes of these intercorrelations using intra-class correlations (ICC). To investigate our main hypotheses, we regressed aggression on the average duration (and average occurrence) of resting-state microstates (data in wide format). We then tested if gender would moderate associations between aggression and average microstate duration (and average microstate occurrence) in Process (Hayes 2017). Moderation analysis tests whether the magnitude or direction of an association between two variables depends on a third variable (i.e., the moderator) by including the interaction between the independent variable and the moderator in the regression term. To analyze any gender-differences in detail, we calculated regression analyses separately in men and women. Finally, we repeated all previous analyses separately for the four subscales of our aggression scale to analyze specific associations of microstate stability with hostility, physicality, verbal aggression, and anger.
Results
Resting-State Microstates
The average EEG time available for microstate analyses was 105.64 s (range 50.94–112.70 s). Consistent with previous studies, the four prototypical microstate types explained an average of 74.71% of variance in EEG signals (range 55.93–84.43%; see Table S1 in the supplementary material for detailed descriptive statistics). Supporting the idea of a stable individual tendency for higher or lower microstate stability across microstate types, a mixed model of general microstate duration including a random intercept across participants resulted in a higher model fit compared to a simple model of general microstate duration (p < 0.001). The same applied for general microstate occurrence (p < 0.001). Intraclass correlations confirmed substantial intercorrelations among durations and occurrences of the four microstate types (durations: ICC = 0.747, occurrences: ICC = 0.729). These results confirm the usefulness of analyzing the mean duration (and the mean occurrence) of resting-state microstates.
Associations of Microstate Stability and Aggression
As hypothesized, mean microstate duration was negatively associated with aggression (β = − 0.265, p = 0.008, R2 = 0.070; see Fig. 1 and Table 2). The subscales physical aggression, verbal aggression and hostility contributed to this effect, but not the subscale anger (see Table 2). Furthermore, mean microstate occurrence was positively associated with aggression (β = 0.312, p = 0.001, R2 = 0.098; see Fig. 1 and Table 2). Again, the subscales physical aggression, verbal aggression and hostility contributed to this effect, but not the subscale anger (see Table 2). In sum, these results suggest that lower microstate stability is associated with aggression. Similar to Kleinert and colleagues (2022), these effects were stable across all four prototypical microstate types (see Table S2 in the supplementary material).
Gender Differences
Using model 1 in the process-macro for moderation analyses (Hayes 2017), we found that the negative association of aggression and mean microstate duration is moderated by gender, with men showing a larger negative association than women (interaction effect: p = 0.045; βmen = − 0.471, pmen = 0.001 vs βwomen = − 0.141, pwomen = 0.290; see Fig. 2 and Table 2; for separate analyses for each microstate type see Table S2 in the supplementary material). The subscales physical aggression and anger contributed to this effect, but not the subscales verbal aggression and hostility (see Table 2). These results demonstrate that the negative association of mean microstate duration and aggression applies primarily to men, and only to a lesser extent to women. Furthermore, we found that the positive association of aggression and mean microstate occurrence is not moderated by gender (interaction effect: p = 0.223; βmen = 0.437, pmen = 0.003 vs βwomen = 0.226, pwomen = 0.088). However, there were significant associations of mean microstate occurrence with aggression (and with the subscales physical aggression, hostility and anger) in men, but not in women. Also note that gender moderated the association of the subscale anger with mean microstate occurrence, with men showing a larger positive association than women.
Discussion
In line with our main hypothesis, shorter durations and more occurrences of microstates, indicating lower microstate stability, were observed in individuals with higher levels of trait aggression. This finding complements previous associations of microstate stability with self-control, inhibitory control and risk-taking (Kleinert et al. 2022). Broadly, our results provide further support for the notion that microstate stability at rest constitutes an important neural source of individual heterogeneity. More specifically, our results illustrate that trait aggression is predicted by the basic temporal organization of the resting brain. Brain areas associated with both trait aggression and resting-state microstates significantly overlap, including the anterior cingulate cortex, the insula, and parts of the prefrontal cortex (MacDonald et al. 2000; Allman et al. 2001; Denson et al. 2009; Figner et al. 2010; Menon and Uddin 2010; Chester et al. 2014; Dambacher et al. 2015; Custo et al. 2017; Milz et al. 2017; Repple et al. 2017; Skibsted et al. 2017). Possibly, more effective functioning of these neural sources at rest contributes to a higher microstate stability as well as a higher capacity to control aggressive impulses, and thus predisposes for lower levels of trait aggression. Indeed, a recent study found that the functional connectivity of resting networks, including both the ACC and the insula, is related to aggressive impulses in combat veterans (Varkevisser et al. 2017). Future studies are needed to further examine this mechanistic framework, e.g., by investigating how microstate stability at rest is related to task-related brain activity associated with aggression, and, importantly, if it causally predicts actual subsequent aggressive behavior.
Based on research demonstrating higher levels of aggression in men compared to women (Zell et al. 2015), as well as gender effects in the expression of aggression (Lagerspetz et al. 1988; Cairns et al. 1989; Buss and Perry 1992; Crick and Grotpeter 1995), we analyzed possible gender-differences in the association between microstate stability and trait aggression. Overall, we found that the association of microstate stability and trait aggression was stronger in men compared to women. To the best of our knowledge, we note that this is the first study to show gender-differences in the functional significance of resting-state microstates. More specifically, our results suggest that trait aggression might be represented by a lower temporal stability of resting networks in men, whereas aggression in women might primarily result from more complex, situational neural mechanisms. This notion is in line with research on the preferred usage of direct forms of aggression in males, and more complex aggressive strategies, such as relational or indirect aggression, in females (Lagerspetz et al. 1988; Crick and Grotpeter 1995). Investigating different facets of aggression, we found that gender differences occurred due to higher associations of microstate stability with physical aggression and anger in men compared to women, but not with verbal aggression or hostility. Physical aggression can be characterized as a typical male way to express aggression (Cairns et al. 1989; item example: "Given enough provocation, I may hit another person"; Buss and Perry 1992) and anger is operationalized in the Aggression Questionnaire as a non-cognitive trait reflecting impulsivity (correlation of anger with impulsivity: r = 0.42; item example: “I flare up quickly but get over it quickly”; Buss and Perry 1992). On the other hand, verbal aggression requires higher order brain functions to engage in language processing (item example: “I can’t help getting into arguments when people disagree with me”; Buss and Perry 1992), and hostility represents a ruminative, cognitively driven trait (item example: “Other people always seem to get the breaks”; Buss and Perry 1992). Thus, our results support the assumption of an easily accessible, microstate driven pathway to aggression in men, which is less pronounced in women (especially concerning physical and impulsive aggression).
In summary, this study provides novel insights into the largely unknown functional significance of resting-state microstates and indicates for the first time that this functional significance might differ between men and women. Based on this study and recent projects (Schiller et al. 2020b; Nash et al. 2022; Kleinert et al. 2022), resting-state microstate characteristics constitute a unique and predictive measure in neural trait research. In particular, resting-state microstate stability provides a task-independent window into individual heterogeneity in fundamental neural network dynamics, and this neural heterogeneity has been associated with key differences at the trait level. This has opened up numerous avenues for important future research. For example, studies are needed to further evaluate origins, mechanics, and functions of microstate stability. More research is also needed to shed light on the exact causal mechanisms that underly associations of resting-state microstates with human traits. Finally, larger and more diverse samples are required to enable investigations of differences in the functional significance of microstates regarding gender, age, culture, education and economic background.
Data Availability
All data and code needed to reproduce the results of this work are freely available online in the OSF repository (https://osf.io/cen3s).
References
Abreu R, Jorge J, Leal A et al (2021) EEG microstates predict concurrent fMRI dynamic functional connectivity states. Brain Topogr 34:41–55
Allman JM, Hakeem A, Erwin JM et al (2001) The anterior cingulate cortex: the evolution of an interface between emotion and cognition. Ann N Y Acad Sci 935:107–117
Anderson CA, Bushman BJ (2002) Human aggression. Annu Rev Psychol 53:27–51
Archer J (2006) Testosterone and human aggression: an evaluation of the challenge hypothesis. Neurosci Biobehav Rev 30:319–345
Archer J (2019) The reality and evolutionary significance of human psychological sex differences. Biol Rev 94:1381–1415
Bandura A (1973) Aggression: a social learning analysis. Prentice-Hall, New York
Barry RJ, Clarke AR, Johnstone SJ et al (2007) EEG differences between eyes-closed and eyes-open resting conditions. Clin Neurophysiol 118:2765–2773
Baumeister RF, Boden JM (1998) Aggression and the self: high self-esteem, low self-control, and ego threat. In: Human aggression. Elsevier, pp 111–137
Baumgartner T, Langenbach BP, Gianotti LRR et al (2019) Frequency of everyday pro-environmental behaviour is explained by baseline activation in lateral prefrontal cortex. Sci Rep 9:1–7
Berkman ET, Falk EB (2013) Beyond brain mapping: Using neural measures to predict real-world outcomes. Curr Dir Psychol Sci 22:45–50
Berkowitz L (1993) Aggression: its causes, consequences, and control. Mcgraw-Hill Book Company, New York
Blair RJR (2001) Neurocognitive models of aggression, the antisocial personality disorders, and psychopathy. J Neurol Neurosurg Psychiatry 71:727–731
Book AS, Starzyk KB, Quinsey VL (2001) The relationship between testosterone and aggression: a meta-analysis. Aggress Violent Behav 6:579–599
Britz J, Van De Ville D, Michel CM (2010) BOLD correlates of EEG topography reveal rapid resting-state network dynamics. Neuroimage 52:1162–1170
Bryant FB, Smith BD (2001) Refining the architecture of aggression: a measurement model for the Buss-Perry Aggression Questionnaire. J Res Personal 35:138–167
Buss AH, Perry M (1992) The aggression questionnaire. J Pers Soc Psychol 63:452
Cairns RB, Cairns BD, Neckerman HJ et al (1989) Growth and aggression: I. Childhood to early adolescence. Dev Psychol 25:320
Campbell A (1999) Staying alive: evolution, culture, and women’s intrasexual aggression. Behav Brain Sci 22:203–214
Chester DS, Eisenberger NI, Pond RS Jr et al (2014) The interactive effect of social pain and executive functioning on aggression: an fMRI experiment. Soc Cogn Affect Neurosci 9:699–704
Cohn A, Zeichner A (2006) Effects of masculine identity and gender role stress on aggression in men. Psychol Men Masculinity 7:179
Crick NR, Grotpeter JK (1995) Relational aggression, gender, and social-psychological adjustment. Child Dev 66:710–722
Custo A, Van De Ville D, Wells WM et al (2017) Electroencephalographic resting-state networks: source localization of microstates. Brain Connect 7:671–682
da Cruz JR, Favrod O, Roinishvili M et al (2020) EEG microstates are a candidate endophenotype for schizophrenia. Nat Commun 11:1–11
Dambacher F, Sack AT, Lobbestael J et al (2015) Out of control: evidence for anterior insula involvement in motor impulsivity and reactive aggression. Soc Cogn Affect Neurosci 10:508–516
Damoiseaux JS, Rombouts S, Barkhof F et al (2006) Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci 103:13848–13853
de Bock R, Mackintosh AJ, Maier F et al (2020) EEG microstates as biomarker for psychosis in ultra-high-risk patients. Transl Psychiatry 10:1–9
Deffenbacher JL, Lynch RS, Oetting ER, Yingling DA (2001) Driving anger: correlates and a test of state-trait theory. Personal Individ Differ 31:1321–1331
Delorme A, Makeig S (2004) EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. J Neurosci Methods 134:9–21
Denson TF, Pedersen WC, Ronquillo J, Nandy AS (2009) The angry brain: neural correlates of anger, angry rumination, and aggressive personality. J Cogn Neurosci 21:734–744
Denson TF, DeWall CN, Finkel EJ (2012) Self-control and aggression. Curr Dir Psychol Sci 21:20–25
DeWall CN, Anderson CA, Bushman BJ (2011a) The general aggression model: theoretical extensions to violence. Psychol Violence 1:245
DeWall CN, Finkel EJ, Denson TF (2011b) Self-control inhibits aggression. Soc Personal Psychol Compass 5:458–472
Douglas SC, Martinko MJ (2001) Exploring the role of individual differences in the prediction of workplace aggression. J Appl Psychol 86:547
Falk Ö, Wallinius M, Lundström S et al (2014) The 1% of the population accountable for 63% of all violent crime convictions. Soc Psychiatry Psychiatr Epidemiol 49:559–571
Falk Ö, Sfendla A, Brändström S et al (2017) Personality and trait aggression profiles of male and female prison inmates. Psychiatry Res 250:302–309
Faul F, Erdfelder E, Buchner A, Lang A-G (2009) Statistical power analyses using G* Power 3.1: tests for correlation and regression analyses. Behav Res Methods 41:1149–1160
Figner B, Knoch D, Johnson EJ et al (2010) Lateral prefrontal cortex and self-control in intertemporal choice. Nat Neurosci 13:538–539
Gosling SD, Rentfrow PJ, Swann WB Jr (2003) A very brief measure of the Big-Five personality domains. J Res Pers 37(6):504–528
Gosling SD, Rentfrow PJ, Potter J (2014) Norms for the ten item personality inventory. Unpublished data. https://gosling.psy.utexas.edu/scales-weve-developed/ten-item-personality-measure-tipi/
Harris JA (1997) A further evaluation of the aggression questionnaire: issues of validity and reliability. Behav Res Ther 35:1047–1053
Hayes AF (2017) Introduction to mediation, moderation, and conditional process analysis: a regression-based approach. Guilford Publications, New York
Khanna A, Pascual-Leone A, Farzan F (2014) Reliability of resting-state microstate features in electroencephalography. PLoS ONE 9:e114163. https://doi.org/10.1371/journal.pone.0114163
Khanna A, Pascual-Leone A, Michel CM, Farzan F (2015) Microstates in resting-state EEG: current status and future directions. Neurosci Biobehav Rev 49:105–113
Kleinert T, Nash K, Leota J et al (2022) A self-controlled mind is reflected by stable mental processing. Psychol Sci: 09567976221110136
Koenig T (2017) EEGLAB plugin manual. In: EEGLAB plugin microstates. http://www.thomaskoenig.ch/index.php/software/10-eeglab-plugin-manual. Accessed 16 March 2022
Koenig T, Prichep L, Lehmann D et al (2002) Millisecond by millisecond, year by year: normative EEG microstates and developmental stages. Neuroimage 16:41–48. https://doi.org/10.1006/nimg.2002.1070
Kuin N, Masthoff E, Kramer M, Scherder E (2015) The role of risky decision-making in aggression: a systematic review. Aggress Violent Behav 25:159–172
Lagerspetz KM, Björkqvist K, Peltonen T (1988) Is indirect aggression typical of females? Gender differences in aggressiveness in 11-to 12-year-old children. Aggress Behav 14:403–414
Lee MH, Smyser CD, Shimony JS (2013) Resting-state fMRI: a review of methods and clinical applications. Am J Neuroradiol 34:1866–1872
Lehmann D, Ozaki H, Pal I (1987) EEG alpha map series: brain micro-states by space-oriented adaptive segmentation. Electroencephalogr Clin Neurophysiol 67:271–288. https://doi.org/10.1016/0013-4694(87)90025-3
Lehmann D, Strik WK, Henggeler B et al (1998) Brain electric microstates and momentary conscious mind states as building blocks of spontaneous thinking: I. Visual imagery and abstract thoughts. Int J Psychophysiol 29:1–11
Leota J, Kleinert T, Tran A, Nash K (2021) Neural signatures of heterogeneity in risk-taking and strategic consistency. Eur J Neurosci 54(9):7214–7230
Liu J, Xu J, Zou G et al (2020) Reliability and individual specificity of EEG microstate characteristics. Brain Topogr 33:438–449
MacDonald AW, Cohen JD, Stenger VA, Carter CS (2000) Dissociating the role of the dorsolateral prefrontal and anterior cingulate cortex in cognitive control. Science 288:1835–1838
Mantini D, Perrucci MG, Del Gratta C et al (2007) Electrophysiological signatures of resting state networks in the human brain. Proc Natl Acad Sci 104:13170–13175
Menon V, Uddin LQ (2010) Saliency, switching, attention and control: a network model of insula function. Brain Struct Funct 214:655–667
Michel CM, Koenig T (2018) EEG microstates as a tool for studying the temporal dynamics of whole-brain neuronal networks: a review. Neuroimage 180:577–593
Michel CM, Koenig T, Brandeis D (2009) Electrical neuroimaging in the time domain. In: Michel CM, Koenig T, Brandeis D et al (eds) Electrical neuroimaging. Cambridge University Press, Cambridge, pp 111–144
Milz P, Pascual-Marqui RD, Achermann P et al (2017) The EEG microstate topography is predominantly determined by intracortical sources in the alpha band. Neuroimage 162:353–361
Moore TM, Stuart GL (2004) Effects of masculine gender role stress on men’s cognitive, affective, physiological, and aggressive responses to intimate conflict situations. Psychol Men Masculinity 5:132
Murray MM, Brunet D, Michel CM (2008) Topographic ERP analyses: a step-by-step tutorial review. Brain Topogr 20:249–264
Musso F, Brinkmeyer J, Mobascher A et al (2010) Spontaneous brain activity and EEG microstates. A novel EEG/fMRI analysis approach to explore resting-state networks. Neuroimage 52:1149–1161
Nash K, Tran A, Leota J, Scott A (2020) Economic threat heightens conflict detection: sLORETA evidence. Soc Cogn Affect Neurosci 15:981–990
Nash K, Leota J, Tran A (2021) Neural processes in antecedent anxiety modulate risk-taking behavior. Sci Rep 11:1–11
Nash K, Kleinert T, Leota J et al (2022) Resting-state networks of believers and non-believers: an EEG microstate study. Biol Psychol 169:108283
Nelson RJ, Trainor BC (2007) Neural mechanisms of aggression. Nat Rev Neurosci 8:536–546
Newson JJ, Thiagarajan TC (2019) EEG frequency bands in psychiatric disorders: a review of resting state studies. Front Hum Neurosci 12:521
Pal A, Behari M, Goyal V, Sharma R (2021) Study of EEG microstates in Parkinson’s disease: a potential biomarker? Cogn Neurodyn 15:463–471
Pawliczek CM, Derntl B, Kellermann T et al (2013) Inhibitory control and trait aggression: neural and behavioral insights using the emotional stop signal task. Neuroimage 79:264–274
Poskanzer C, Denis D, Herrick A, Stickgold R (2021) Using EEG microstates to examine post-encoding quiet rest and subsequent word-pair memory. Neurobiol Learn Mem 181:107424
Puts D (2016) Human sexual selection. Curr Opin Psychol 7:28–32
Raaijmakers MA, Smidts DP, Sergeant JA et al (2008) Executive functions in preschool children with aggressive behavior: impairments in inhibitory control. J Abnorm Child Psychol 36:1097–1107
Repple J, Pawliczek CM, Voss B et al (2017) From provocation to aggression: the neural network. BMC Neurosci 18:1–9
Ruddle A, Pina A, Vasquez E (2017) Domestic violence offending behaviors: a review of the literature examining childhood exposure, implicit theories, trait aggression and anger rumination as predictive factors. Aggress Violent Behav 34:154–165
Schiller B, Gianotti LRR, Nash K, Knoch D (2014) Individual differences in inhibitory control—relationship between baseline activation in lateral pfc and an electrophysiological index of response inhibition. Cereb Cortex 24:2430–2435. https://doi.org/10.1093/cercor/bht095
Schiller B, Gianotti LRR, Baumgartner T, Knoch D (2019) Theta resting EEG in the right TPJ is associated with individual differences in implicit intergroup bias. Soc Cogn Affect Neurosci 14:281–289
Schiller B, Domes G, Heinrichs M (2020a) Oxytocin changes behavior and spatio-temporal brain dynamics underlying inter-group conflict in humans. Eur Neuropsychopharmacol 31:119–130
Schiller B, Kleinert T, Teige-Mocigemba S et al (2020b) Temporal dynamics of resting EEG networks are associated with prosociality. Sci Rep 10:13066. https://doi.org/10.1038/s41598-020-69999-5
Schiller B, Heinrichs M, Beste C, Stock A-K (2021) Acute alcohol intoxication modulates the temporal dynamics of resting electroencephalography networks. Addict Biol 26(6):e13034
Schlegel F, Lehmann D, Faber PL et al (2012) EEG microstates during resting represent personality differences. Brain Topogr 25:20–26
Skibsted AP, da Cunha-Bang S, Carré JM et al (2017) Aggression-related brain function assessed with the Point Subtraction Aggression Paradigm in fMRI. Aggress Behav 43:601–610
Strik WK, Lehmann D (1993) Data-determined window size and space-oriented segmentation of spontaneous EEG map series. Electroencephalogr Clin Neurophysiol 87:169–174
Stucke TS, Baumeister RF (2006) Ego depletion and aggressive behavior: is the inhibition of aggression a limited resource? Eur J Soc Psychol 36:1–13
Tomescu MI, Rihs TA, Rochas V et al (2018) From swing to cane: sex differences of EEG resting-state temporal patterns during maturation and aging. Dev Cogn Neurosci 31:58–66
Twenge JM, Campbell WK (2003) “Isn’t it fun to get the respect that we’re going to deserve?” Narcissism, social rejection, and aggression. Pers Soc Psychol Bull 29:261–272
Twenge JM, Baumeister RF, Tice DM, Stucke TS (2001) If you can’t join them, beat them: effects of social exclusion on aggressive behavior. J Pers Soc Psychol 81:1058
Van de Ville D, Britz J, Michel CM (2010) EEG microstate sequences in healthy humans at rest reveal scale-free dynamics. Proc Natl Acad Sci 107:18179–18184
Varkevisser T, Gladwin TE, Heesink L et al (2017) Resting-state functional connectivity in combat veterans suffering from impulsive aggression. Soc Cogn Affect Neurosci 12:1881–1889
Wackermann J, Lehmann D, Michel CM, Strik WK (1993) Adaptive segmentation of spontaneous EEG map series into spatially defined microstates. Int J Psychophysiol 14:269–283
Wilkowski BM, Robinson MD (2008) The cognitive basis of trait anger and reactive aggression: an integrative analysis. Personal Soc Psychol Rev 12:3–21
Yuan H, Zotev V, Phillips R et al (2012) Spatiotemporal dynamics of the brain at rest—exploring EEG microstates as electrophysiological signatures of BOLD resting state networks. Neuroimage 60:2062–2072
Zanesco AP, King BG, Skwara AC, Saron CD (2020) Within and between-person correlates of the temporal dynamics of resting EEG microstates. Neuroimage 211:116631
Zell E, Krizan Z, Teeter SR (2015) Evaluating gender similarities and differences using metasynthesis. Am Psychol 70:10
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CRediT author statement Tobias Kleinert: Conceptualization, Methodology, Software, Formal Analysis, Data Curation, Writing - Original Draft, Visualization. Kyle Nash: Conceptualization, Methodology, Investigation, Resources, Writing - Review & Editing, Supervision, Project Administration.
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Kleinert, T., Nash, K. Trait Aggression is Reflected by a Lower Temporal Stability of EEG Resting Networks. Brain Topogr 37, 514–523 (2024). https://doi.org/10.1007/s10548-022-00929-6
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DOI: https://doi.org/10.1007/s10548-022-00929-6